PPP1R16A-ADCK5 Fusion FISH Probe
The PPP1R16A-ADCK5 Fusion FISH Probe is used to confirm a fusion of the PPP1R16A and ADCK5 genes. The fusion of the PPP1R16A and ADCK5 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PPP1R16A-ADCK5-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PPP1R16A-ADCK5-20-RERE | 20 (40 μL) | 200 μL |
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| PPP1R16A-ADCK5-20-REOR | 20 (40 μL) | 200 μL |
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| PPP1R16A-ADCK5-20-REGO | 20 (40 μL) | 200 μL |
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| PPP1R16A-ADCK5-20-REGR | 20 (40 μL) | 200 μL |
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| PPP1R16A-ADCK5-20-REAQ | 20 (40 μL) | 200 μL |
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| PPP1R16A-ADCK5-20-ORRE | 20 (40 μL) | 200 μL |
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| PPP1R16A-ADCK5-20-OROR | 20 (40 μL) | 200 μL |
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| PPP1R16A-ADCK5-20-ORGO | 20 (40 μL) | 200 μL |
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| PPP1R16A-ADCK5-20-ORAQ | 20 (40 μL) | 200 μL |
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| PPP1R16A-ADCK5-20-GORE | 20 (40 μL) | 200 μL |
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| PPP1R16A-ADCK5-20-GOOR | 20 (40 μL) | 200 μL |
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| PPP1R16A-ADCK5-20-GOGO | 20 (40 μL) | 200 μL |
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| PPP1R16A-ADCK5-20-GOGR | 20 (40 μL) | 200 μL |
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| PPP1R16A-ADCK5-20-GOAQ | 20 (40 μL) | 200 μL |
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| PPP1R16A-ADCK5-20-GRRE | 20 (40 μL) | 200 μL |
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| PPP1R16A-ADCK5-20-GROR | 20 (40 μL) | 200 μL |
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| PPP1R16A-ADCK5-20-GRGO | 20 (40 μL) | 200 μL |
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| PPP1R16A-ADCK5-20-GRGR | 20 (40 μL) | 200 μL |
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| PPP1R16A-ADCK5-20-GRAQ | 20 (40 μL) | 200 μL |
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| PPP1R16A-ADCK5-20-AQRE | 20 (40 μL) | 200 μL |
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| PPP1R16A-ADCK5-20-AQOR | 20 (40 μL) | 200 μL |
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| PPP1R16A-ADCK5-20-AQGO | 20 (40 μL) | 200 μL |
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| PPP1R16A-ADCK5-20-AQGR | 20 (40 μL) | 200 μL |
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| PPP1R16A-ADCK5-20-AQAQ | 20 (40 μL) | 200 μL |
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PPP1R16A Gene Summary
Myosin light chain kinase and phosphatase (MLCP) complexes control the phosphorylation states of regulatory myosin light chains, which is crucial for muscle and intracellular movement. MLCPs typically contain a catalytic protein phosphatase 1 (PP1c) subunit, a myosin phosphatase targeting (MYPT) subunit, and another smaller subunit. The protein encoded by this gene represents an MYPT subunit, which is responsible for directing PP1c to its intended targets. However, while other MYPTs result in PP1c activation after becoming phosphorylated, the encoded protein is phosphorylated by protein kinase A and then inhibits the catalytic activity of PP1c. [provided by RefSeq, Jul 2016]
Gene Name: Protein Phosphatase 1 Regulatory Subunit 16A
Chromosome: CHR8: 145722108 -145727504
Locus: 8q24.3
ADCK5 Gene Summary
The AarF Domain Containing Kinase 5 (ADCK5) gene is located on chr8 :145597730-145618453 at 8q24.3.
Gene Name: AarF Domain Containing Kinase 5
Chromosome: CHR8: 145597730 -145618453
Locus: 8q24.3
Gene Diseases
The PPP1R16A ADCK5 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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