PPP1R13B-C14ORF2 Fusion FISH Probe
The PPP1R13B-C14ORF2 Fusion FISH Probe is used to confirm a fusion of the PPP1R13B and C14ORF2 genes. The fusion of the PPP1R13B and C14ORF2 genes has been associated with Uterine Corpus Endometrial Carcinoma, and Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PPP1R13B-C14ORF2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PPP1R13B-C14ORF2-20-RERE | 20 (40 μL) | 200 μL |
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| PPP1R13B-C14ORF2-20-REOR | 20 (40 μL) | 200 μL |
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| PPP1R13B-C14ORF2-20-REGO | 20 (40 μL) | 200 μL |
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| PPP1R13B-C14ORF2-20-REGR | 20 (40 μL) | 200 μL |
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| PPP1R13B-C14ORF2-20-REAQ | 20 (40 μL) | 200 μL |
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| PPP1R13B-C14ORF2-20-ORRE | 20 (40 μL) | 200 μL |
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| PPP1R13B-C14ORF2-20-OROR | 20 (40 μL) | 200 μL |
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| PPP1R13B-C14ORF2-20-ORGO | 20 (40 μL) | 200 μL |
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| PPP1R13B-C14ORF2-20-ORAQ | 20 (40 μL) | 200 μL |
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| PPP1R13B-C14ORF2-20-GORE | 20 (40 μL) | 200 μL |
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| PPP1R13B-C14ORF2-20-GOOR | 20 (40 μL) | 200 μL |
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| PPP1R13B-C14ORF2-20-GOGO | 20 (40 μL) | 200 μL |
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| PPP1R13B-C14ORF2-20-GOGR | 20 (40 μL) | 200 μL |
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| PPP1R13B-C14ORF2-20-GOAQ | 20 (40 μL) | 200 μL |
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| PPP1R13B-C14ORF2-20-GRRE | 20 (40 μL) | 200 μL |
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| PPP1R13B-C14ORF2-20-GROR | 20 (40 μL) | 200 μL |
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| PPP1R13B-C14ORF2-20-GRGO | 20 (40 μL) | 200 μL |
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| PPP1R13B-C14ORF2-20-GRGR | 20 (40 μL) | 200 μL |
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| PPP1R13B-C14ORF2-20-GRAQ | 20 (40 μL) | 200 μL |
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| PPP1R13B-C14ORF2-20-AQRE | 20 (40 μL) | 200 μL |
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| PPP1R13B-C14ORF2-20-AQOR | 20 (40 μL) | 200 μL |
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| PPP1R13B-C14ORF2-20-AQGO | 20 (40 μL) | 200 μL |
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| PPP1R13B-C14ORF2-20-AQGR | 20 (40 μL) | 200 μL |
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| PPP1R13B-C14ORF2-20-AQAQ | 20 (40 μL) | 200 μL |
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C14orf2 Gene Summary
The Chromosome 14 Open Reading Frame 2 (C14orf2) gene is located on chr14 :104378624-104387903 at 14q32.33.
Gene Name: Chromosome 14 Open Reading Frame 2
Chromosome: CHR14: 104378624 -104387903
Locus: 14q32.33
PPP1R13B Gene Summary
This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. ASPP proteins are required for the induction of apoptosis by p53-family proteins. They promote DNA binding and transactivation of p53-family proteins on the promoters of proapoptotic genes. Expression of this gene is regulated by the E2F transcription factor. [provided by RefSeq, Jul 2008]
Gene Name: Protein Phosphatase 1 Regulatory Subunit 13B
Chromosome: CHR14: 104200087 -104313927
Locus: 14q32.33
Gene Diseases
The PPP1R13B C14ORF2 Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Corpus Endometrial Carcinoma |
| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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