PPME1-YIF1A Fusion FISH Probe
The PPME1-YIF1A Fusion FISH Probe is used to confirm a fusion of the PPME1 and YIF1A genes. The fusion of the PPME1 and YIF1A genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PPME1-YIF1A-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PPME1-YIF1A-20-RERE | 20 (40 μL) | 200 μL |
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| PPME1-YIF1A-20-REOR | 20 (40 μL) | 200 μL |
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| PPME1-YIF1A-20-REGO | 20 (40 μL) | 200 μL |
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| PPME1-YIF1A-20-REGR | 20 (40 μL) | 200 μL |
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| PPME1-YIF1A-20-REAQ | 20 (40 μL) | 200 μL |
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| PPME1-YIF1A-20-ORRE | 20 (40 μL) | 200 μL |
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| PPME1-YIF1A-20-OROR | 20 (40 μL) | 200 μL |
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| PPME1-YIF1A-20-ORGO | 20 (40 μL) | 200 μL |
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| PPME1-YIF1A-20-ORAQ | 20 (40 μL) | 200 μL |
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| PPME1-YIF1A-20-GORE | 20 (40 μL) | 200 μL |
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| PPME1-YIF1A-20-GOOR | 20 (40 μL) | 200 μL |
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| PPME1-YIF1A-20-GOGO | 20 (40 μL) | 200 μL |
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| PPME1-YIF1A-20-GOGR | 20 (40 μL) | 200 μL |
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| PPME1-YIF1A-20-GOAQ | 20 (40 μL) | 200 μL |
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| PPME1-YIF1A-20-GRRE | 20 (40 μL) | 200 μL |
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| PPME1-YIF1A-20-GROR | 20 (40 μL) | 200 μL |
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| PPME1-YIF1A-20-GRGO | 20 (40 μL) | 200 μL |
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| PPME1-YIF1A-20-GRGR | 20 (40 μL) | 200 μL |
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| PPME1-YIF1A-20-GRAQ | 20 (40 μL) | 200 μL |
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| PPME1-YIF1A-20-AQRE | 20 (40 μL) | 200 μL |
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| PPME1-YIF1A-20-AQOR | 20 (40 μL) | 200 μL |
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| PPME1-YIF1A-20-AQGO | 20 (40 μL) | 200 μL |
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| PPME1-YIF1A-20-AQGR | 20 (40 μL) | 200 μL |
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| PPME1-YIF1A-20-AQAQ | 20 (40 μL) | 200 μL |
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YIF1A Gene Summary
The Yip1 Interacting Factor Homolog A, Membrane Trafficking Protein (YIF1A) gene is located on chr11 :66052050-66056638 at 11q13.2.
Gene Name: Yip1 Interacting Factor Homolog A, Membrane Trafficking Protein
Chromosome: CHR11: 66052050 -66056638
Locus: 11q13.2
PPME1 Gene Summary
This gene encodes a protein phosphatase methylesterase localized to the nucleus. The encoded protein acts on the protein phosphatase-2A catalytic subunit and supports the ERK pathway through dephosphorylation of regulatory proteins. It plays a role in malignant glioma progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012]
Gene Name: Protein Phosphatase Methylesterase 1
Chromosome: CHR11: 73882367 -73965748
Locus: 11q13.4
Gene Diseases
The PPME1 YIF1A Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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