PPM1H-WIF1 Fusion FISH Probe
The PPM1H-WIF1 Fusion FISH Probe is used to confirm a fusion of the PPM1H and WIF1 genes. The fusion of the PPM1H and WIF1 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PPM1H-WIF1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PPM1H-WIF1-20-RERE | 20 (40 μL) | 200 μL |
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| PPM1H-WIF1-20-REOR | 20 (40 μL) | 200 μL |
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| PPM1H-WIF1-20-REGO | 20 (40 μL) | 200 μL |
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| PPM1H-WIF1-20-REGR | 20 (40 μL) | 200 μL |
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| PPM1H-WIF1-20-REAQ | 20 (40 μL) | 200 μL |
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| PPM1H-WIF1-20-ORRE | 20 (40 μL) | 200 μL |
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| PPM1H-WIF1-20-OROR | 20 (40 μL) | 200 μL |
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| PPM1H-WIF1-20-ORGO | 20 (40 μL) | 200 μL |
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| PPM1H-WIF1-20-ORAQ | 20 (40 μL) | 200 μL |
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| PPM1H-WIF1-20-GORE | 20 (40 μL) | 200 μL |
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| PPM1H-WIF1-20-GOOR | 20 (40 μL) | 200 μL |
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| PPM1H-WIF1-20-GOGO | 20 (40 μL) | 200 μL |
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| PPM1H-WIF1-20-GOGR | 20 (40 μL) | 200 μL |
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| PPM1H-WIF1-20-GOAQ | 20 (40 μL) | 200 μL |
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| PPM1H-WIF1-20-GRRE | 20 (40 μL) | 200 μL |
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| PPM1H-WIF1-20-GROR | 20 (40 μL) | 200 μL |
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| PPM1H-WIF1-20-GRGO | 20 (40 μL) | 200 μL |
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| PPM1H-WIF1-20-GRGR | 20 (40 μL) | 200 μL |
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| PPM1H-WIF1-20-GRAQ | 20 (40 μL) | 200 μL |
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| PPM1H-WIF1-20-AQRE | 20 (40 μL) | 200 μL |
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| PPM1H-WIF1-20-AQOR | 20 (40 μL) | 200 μL |
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| PPM1H-WIF1-20-AQGO | 20 (40 μL) | 200 μL |
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| PPM1H-WIF1-20-AQGR | 20 (40 μL) | 200 μL |
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| PPM1H-WIF1-20-AQAQ | 20 (40 μL) | 200 μL |
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WIF1 Gene Summary
The protein encoded by this gene functions to inhibit WNT proteins, which are extracellular signaling molecules that play a role in embryonic development. This protein contains a WNT inhibitory factor (WIF) domain and five epidermal growth factor (EGF)-like domains, and is thought to be involved in mesoderm segmentation. This gene functions as a tumor suppressor gene, and has been found to be epigenetically silenced in various cancers. [provided by RefSeq, Jun 2010]
Gene Name: WNT Inhibitory Factor 1
Chromosome: CHR12: 65444403 -65515346
Locus: 12q14.3
PPM1H Gene Summary
The Protein Phosphatase, Mg2+/Mn2+ Dependent 1H (PPM1H) gene is located on chr12 :63037762-63328665 at 12q14.1-q14.2.
Gene Name: Protein Phosphatase, Mg2+/Mn2+ Dependent 1H
Chromosome: CHR12: 63037762 -63328665
Locus: 12q14.1-q14.2
Gene Diseases
The PPM1H WIF1 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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