PPM1E-SPAG5 Fusion FISH Probe
The PPM1E-SPAG5 Fusion FISH Probe is used to confirm a fusion of the PPM1E and SPAG5 genes. The fusion of the PPM1E and SPAG5 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PPM1E-SPAG5-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PPM1E-SPAG5-20-RERE | 20 (40 μL) | 200 μL |
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| PPM1E-SPAG5-20-REOR | 20 (40 μL) | 200 μL |
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| PPM1E-SPAG5-20-REGO | 20 (40 μL) | 200 μL |
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| PPM1E-SPAG5-20-REGR | 20 (40 μL) | 200 μL |
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| PPM1E-SPAG5-20-REAQ | 20 (40 μL) | 200 μL |
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| PPM1E-SPAG5-20-ORRE | 20 (40 μL) | 200 μL |
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| PPM1E-SPAG5-20-OROR | 20 (40 μL) | 200 μL |
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| PPM1E-SPAG5-20-ORGO | 20 (40 μL) | 200 μL |
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| PPM1E-SPAG5-20-ORAQ | 20 (40 μL) | 200 μL |
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| PPM1E-SPAG5-20-GORE | 20 (40 μL) | 200 μL |
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| PPM1E-SPAG5-20-GOOR | 20 (40 μL) | 200 μL |
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| PPM1E-SPAG5-20-GOGO | 20 (40 μL) | 200 μL |
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| PPM1E-SPAG5-20-GOGR | 20 (40 μL) | 200 μL |
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| PPM1E-SPAG5-20-GOAQ | 20 (40 μL) | 200 μL |
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| PPM1E-SPAG5-20-GRRE | 20 (40 μL) | 200 μL |
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| PPM1E-SPAG5-20-GROR | 20 (40 μL) | 200 μL |
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| PPM1E-SPAG5-20-GRGO | 20 (40 μL) | 200 μL |
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| PPM1E-SPAG5-20-GRGR | 20 (40 μL) | 200 μL |
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| PPM1E-SPAG5-20-GRAQ | 20 (40 μL) | 200 μL |
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| PPM1E-SPAG5-20-AQRE | 20 (40 μL) | 200 μL |
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| PPM1E-SPAG5-20-AQOR | 20 (40 μL) | 200 μL |
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| PPM1E-SPAG5-20-AQGO | 20 (40 μL) | 200 μL |
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| PPM1E-SPAG5-20-AQGR | 20 (40 μL) | 200 μL |
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| PPM1E-SPAG5-20-AQAQ | 20 (40 μL) | 200 μL |
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SPAG5 Gene Summary
This gene encodes a protein associated with the mitotic spindle apparatus. The encoded protein may be involved in the functional and dynamic regulation of mitotic spindles. [provided by RefSeq, Jul 2008]
Gene Name: Sperm Associated Antigen 5
Chromosome: CHR17: 26904582 -26926056
Locus: 17q11.2
PPM1E Gene Summary
This gene encodes a member of the PPM family of serine/threonine-protein phosphatases. The encoded protein is localized to the nucleus and dephosphorylates and inactivates multiple substrates including serine/threonine-protein kinase PAK 1, 5'-AMP-activated protein kinase (AMPK) and the multifunctional calcium/calmodulin-dependent protein kinases. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, May 2012]
Gene Name: Protein Phosphatase, Mg2+/Mn2+ Dependent 1E
Chromosome: CHR17: 56833231 -57062534
Locus: 17q22
Gene Diseases
The PPM1E SPAG5 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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