PPFIBP1-WNT7A Fusion FISH Probe
The PPFIBP1-WNT7A Fusion FISH Probe is used to confirm a fusion of the PPFIBP1 and WNT7A genes. The fusion of the PPFIBP1 and WNT7A genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PPFIBP1-WNT7A-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PPFIBP1-WNT7A-20-RERE | 20 (40 μL) | 200 μL |
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| PPFIBP1-WNT7A-20-REOR | 20 (40 μL) | 200 μL |
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| PPFIBP1-WNT7A-20-REGO | 20 (40 μL) | 200 μL |
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| PPFIBP1-WNT7A-20-REGR | 20 (40 μL) | 200 μL |
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| PPFIBP1-WNT7A-20-REAQ | 20 (40 μL) | 200 μL |
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| PPFIBP1-WNT7A-20-ORRE | 20 (40 μL) | 200 μL |
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| PPFIBP1-WNT7A-20-OROR | 20 (40 μL) | 200 μL |
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| PPFIBP1-WNT7A-20-ORGO | 20 (40 μL) | 200 μL |
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| PPFIBP1-WNT7A-20-ORAQ | 20 (40 μL) | 200 μL |
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| PPFIBP1-WNT7A-20-GORE | 20 (40 μL) | 200 μL |
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| PPFIBP1-WNT7A-20-GOOR | 20 (40 μL) | 200 μL |
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| PPFIBP1-WNT7A-20-GOGO | 20 (40 μL) | 200 μL |
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| PPFIBP1-WNT7A-20-GOGR | 20 (40 μL) | 200 μL |
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| PPFIBP1-WNT7A-20-GOAQ | 20 (40 μL) | 200 μL |
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| PPFIBP1-WNT7A-20-GRRE | 20 (40 μL) | 200 μL |
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| PPFIBP1-WNT7A-20-GROR | 20 (40 μL) | 200 μL |
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| PPFIBP1-WNT7A-20-GRGO | 20 (40 μL) | 200 μL |
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| PPFIBP1-WNT7A-20-GRGR | 20 (40 μL) | 200 μL |
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| PPFIBP1-WNT7A-20-GRAQ | 20 (40 μL) | 200 μL |
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| PPFIBP1-WNT7A-20-AQRE | 20 (40 μL) | 200 μL |
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| PPFIBP1-WNT7A-20-AQOR | 20 (40 μL) | 200 μL |
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| PPFIBP1-WNT7A-20-AQGO | 20 (40 μL) | 200 μL |
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| PPFIBP1-WNT7A-20-AQGR | 20 (40 μL) | 200 μL |
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| PPFIBP1-WNT7A-20-AQAQ | 20 (40 μL) | 200 μL |
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WNT7A Gene Summary
This gene is a member of the WNT gene family, which consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is involved in the development of the anterior-posterior axis in the female reproductive tract, and also plays a critical role in uterine smooth muscle pattering and maintenance of adult uterine function. Mutations in this gene are associated with Fuhrmann and Al-Awadi/Raas-Rothschild/Schinzel phocomelia syndromes. [provided by RefSeq, Jul 2008]
Gene Name: Wnt Family Member 7A
Chromosome: CHR3: 13860081 -13921618
Locus: 3p25.1
PPFIBP1 Gene Summary
The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. It has been proposed that liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR family of tyrosine phosphatases. This protein was found to interact with S100A4, a calcium-binding protein related to tumor invasiveness and metastasis. In vitro experiment demonstrated that the interaction inhibited the phosphorylation of this protein by protein kinase C and protein kinase CK2. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
Gene Name: PPFIA Binding Protein 1
Chromosome: CHR12: 27677044 -27848497
Locus: 12p11.23-p11.22
Gene Diseases
The PPFIBP1 WNT7A Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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