PPFIBP1-PDILT Fusion FISH Probe
The PPFIBP1-PDILT Fusion FISH Probe is used to confirm a fusion of the PPFIBP1 and PDILT genes. The fusion of the PPFIBP1 and PDILT genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PPFIBP1-PDILT-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| PPFIBP1-PDILT-20-RERE | 20 (40 μL) | 200 μL |
|
|
| PPFIBP1-PDILT-20-REOR | 20 (40 μL) | 200 μL |
|
|
| PPFIBP1-PDILT-20-REGO | 20 (40 μL) | 200 μL |
|
|
| PPFIBP1-PDILT-20-REGR | 20 (40 μL) | 200 μL |
|
|
| PPFIBP1-PDILT-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| PPFIBP1-PDILT-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| PPFIBP1-PDILT-20-OROR | 20 (40 μL) | 200 μL |
|
|
| PPFIBP1-PDILT-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| PPFIBP1-PDILT-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| PPFIBP1-PDILT-20-GORE | 20 (40 μL) | 200 μL |
|
|
| PPFIBP1-PDILT-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| PPFIBP1-PDILT-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| PPFIBP1-PDILT-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| PPFIBP1-PDILT-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| PPFIBP1-PDILT-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| PPFIBP1-PDILT-20-GROR | 20 (40 μL) | 200 μL |
|
|
| PPFIBP1-PDILT-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| PPFIBP1-PDILT-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| PPFIBP1-PDILT-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| PPFIBP1-PDILT-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| PPFIBP1-PDILT-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| PPFIBP1-PDILT-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| PPFIBP1-PDILT-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| PPFIBP1-PDILT-20-AQAQ | 20 (40 μL) | 200 μL |
|
PPFIBP1 Gene Summary
The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. It has been proposed that liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR family of tyrosine phosphatases. This protein was found to interact with S100A4, a calcium-binding protein related to tumor invasiveness and metastasis. In vitro experiment demonstrated that the interaction inhibited the phosphorylation of this protein by protein kinase C and protein kinase CK2. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
Gene Name: PPFIA Binding Protein 1
Chromosome: CHR12: 27677044 -27848497
Locus: 12p11.23-p11.22
PDILT Gene Summary
This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has has an N-terminal ER-signal sequence, two thioredoxin (TRX) domains with non-classical Ser-Lys-Gln-Ser and Ser-Lys-Lys-Cys motifs, respectively, two TRX-like domains, and a C-terminal ER-retention sequence. The protein lacks oxidoreductase activity in vitro and probably functions as a chaperone. This gene's expression appears to be limited to the testis. [provided by RefSeq, Dec 2016]
Gene Name: Protein Disulfide Isomerase Like, Testis Expressed
Chromosome: CHR16: 20370491 -20416033
Locus: 16p12.3
Gene Diseases
The PPFIBP1 PDILT Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|