PPFIA3-IZUMO1 Fusion FISH Probe
The PPFIA3-IZUMO1 Fusion FISH Probe is used to confirm a fusion of the PPFIA3 and IZUMO1 genes. The fusion of the PPFIA3 and IZUMO1 genes has been associated with Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PPFIA3-IZUMO1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PPFIA3-IZUMO1-20-RERE | 20 (40 μL) | 200 μL |
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| PPFIA3-IZUMO1-20-REOR | 20 (40 μL) | 200 μL |
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| PPFIA3-IZUMO1-20-REGO | 20 (40 μL) | 200 μL |
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| PPFIA3-IZUMO1-20-REGR | 20 (40 μL) | 200 μL |
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| PPFIA3-IZUMO1-20-REAQ | 20 (40 μL) | 200 μL |
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| PPFIA3-IZUMO1-20-ORRE | 20 (40 μL) | 200 μL |
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| PPFIA3-IZUMO1-20-OROR | 20 (40 μL) | 200 μL |
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| PPFIA3-IZUMO1-20-ORGO | 20 (40 μL) | 200 μL |
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| PPFIA3-IZUMO1-20-ORAQ | 20 (40 μL) | 200 μL |
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| PPFIA3-IZUMO1-20-GORE | 20 (40 μL) | 200 μL |
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| PPFIA3-IZUMO1-20-GOOR | 20 (40 μL) | 200 μL |
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| PPFIA3-IZUMO1-20-GOGO | 20 (40 μL) | 200 μL |
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| PPFIA3-IZUMO1-20-GOGR | 20 (40 μL) | 200 μL |
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| PPFIA3-IZUMO1-20-GOAQ | 20 (40 μL) | 200 μL |
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| PPFIA3-IZUMO1-20-GRRE | 20 (40 μL) | 200 μL |
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| PPFIA3-IZUMO1-20-GROR | 20 (40 μL) | 200 μL |
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| PPFIA3-IZUMO1-20-GRGO | 20 (40 μL) | 200 μL |
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| PPFIA3-IZUMO1-20-GRGR | 20 (40 μL) | 200 μL |
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| PPFIA3-IZUMO1-20-GRAQ | 20 (40 μL) | 200 μL |
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| PPFIA3-IZUMO1-20-AQRE | 20 (40 μL) | 200 μL |
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| PPFIA3-IZUMO1-20-AQOR | 20 (40 μL) | 200 μL |
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| PPFIA3-IZUMO1-20-AQGO | 20 (40 μL) | 200 μL |
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| PPFIA3-IZUMO1-20-AQGR | 20 (40 μL) | 200 μL |
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| PPFIA3-IZUMO1-20-AQAQ | 20 (40 μL) | 200 μL |
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PPFIA3 Gene Summary
The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. Liprin family protein has been shown to localize phosphatase LAR to cell focal adhesions and may be involved in the molecular organization of presynaptic active zones. [provided by RefSeq, Jul 2008]
Gene Name: PTPRF Interacting Protein Alpha 3
Chromosome: CHR19: 49622662 -49654280
Locus: 19q13.33
IZUMO1 Gene Summary
The sperm-specific protein Izumo, named for a Japanese shrine dedicated to marriage, is essential for sperm-egg plasma membrane binding and fusion (Inoue et al., 2005 [PubMed 15759005]).[supplied by OMIM, Mar 2008]
Gene Name: Izumo Sperm-egg Fusion 1
Chromosome: CHR19: 49244144 -49250166
Locus: 19q13.33
Gene Diseases
The PPFIA3 IZUMO1 Fusion has been associated with the following diseases:
| Disease Name |
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| Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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