PPARGC1B-IL17B Fusion FISH Probe
The PPARGC1B-IL17B Fusion FISH Probe is used to confirm a fusion of the PPARGC1B and IL17B genes. The fusion of the PPARGC1B and IL17B genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PPARGC1B-IL17B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PPARGC1B-IL17B-20-RERE | 20 (40 μL) | 200 μL |
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| PPARGC1B-IL17B-20-REOR | 20 (40 μL) | 200 μL |
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| PPARGC1B-IL17B-20-REGO | 20 (40 μL) | 200 μL |
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| PPARGC1B-IL17B-20-REGR | 20 (40 μL) | 200 μL |
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| PPARGC1B-IL17B-20-REAQ | 20 (40 μL) | 200 μL |
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| PPARGC1B-IL17B-20-ORRE | 20 (40 μL) | 200 μL |
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| PPARGC1B-IL17B-20-OROR | 20 (40 μL) | 200 μL |
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| PPARGC1B-IL17B-20-ORGO | 20 (40 μL) | 200 μL |
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| PPARGC1B-IL17B-20-ORAQ | 20 (40 μL) | 200 μL |
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| PPARGC1B-IL17B-20-GORE | 20 (40 μL) | 200 μL |
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| PPARGC1B-IL17B-20-GOOR | 20 (40 μL) | 200 μL |
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| PPARGC1B-IL17B-20-GOGO | 20 (40 μL) | 200 μL |
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| PPARGC1B-IL17B-20-GOGR | 20 (40 μL) | 200 μL |
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| PPARGC1B-IL17B-20-GOAQ | 20 (40 μL) | 200 μL |
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| PPARGC1B-IL17B-20-GRRE | 20 (40 μL) | 200 μL |
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| PPARGC1B-IL17B-20-GROR | 20 (40 μL) | 200 μL |
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| PPARGC1B-IL17B-20-GRGO | 20 (40 μL) | 200 μL |
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| PPARGC1B-IL17B-20-GRGR | 20 (40 μL) | 200 μL |
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| PPARGC1B-IL17B-20-GRAQ | 20 (40 μL) | 200 μL |
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| PPARGC1B-IL17B-20-AQRE | 20 (40 μL) | 200 μL |
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| PPARGC1B-IL17B-20-AQOR | 20 (40 μL) | 200 μL |
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| PPARGC1B-IL17B-20-AQGO | 20 (40 μL) | 200 μL |
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| PPARGC1B-IL17B-20-AQGR | 20 (40 μL) | 200 μL |
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| PPARGC1B-IL17B-20-AQAQ | 20 (40 μL) | 200 μL |
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IL17B Gene Summary
The protein encoded by this gene is a T cell-derived cytokine that shares sequence similarity with IL17. This cytokine was reported to stimulate the release of TNF alpha (TNF) and IL1 beta (IL1B) from a monocytic cell line. Immunohistochemical analysis of several nerve tissues indicated that this cytokine is primarily localized to neuronal cell bodies. Alternative splicing results in multiple splice variants. [provided by RefSeq, Dec 2015]
Gene Name: Interleukin 17B
Chromosome: CHR5: 148753829 -148758838
Locus: 5q32
PPARGC1B Gene Summary
The protein encoded by this gene stimulates the activity of several transcription factors and nuclear receptors, including estrogen receptor alpha, nuclear respiratory factor 1, and glucocorticoid receptor. The encoded protein may be involved in fat oxidation, non-oxidative glucose metabolism, and the regulation of energy expenditure. This protein is downregulated in prediabetic and type 2 diabetes mellitus patients. Certain allelic variations in this gene increase the risk of the development of obesity. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]
Gene Name: PPARG Coactivator 1 Beta
Chromosome: CHR5: 149109814 -149234585
Locus: 5q32
Gene Diseases
The PPARGC1B IL17B Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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