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PPARGC1B-ARHGEF37 Fusion FISH Probe

The PPARGC1B-ARHGEF37 Fusion FISH Probe is used to confirm a fusion of the PPARGC1B and ARHGEF37 genes. The fusion of the PPARGC1B and ARHGEF37 genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
PPARGC1B-ARHGEF37-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
PPARGC1B-ARHGEF37-20-RERE 20 (40 μL) 200 μL
PPARGC1B-ARHGEF37-20-REOR 20 (40 μL) 200 μL
PPARGC1B-ARHGEF37-20-REGO 20 (40 μL) 200 μL
PPARGC1B-ARHGEF37-20-REGR 20 (40 μL) 200 μL
PPARGC1B-ARHGEF37-20-REAQ 20 (40 μL) 200 μL
PPARGC1B-ARHGEF37-20-ORRE 20 (40 μL) 200 μL
PPARGC1B-ARHGEF37-20-OROR 20 (40 μL) 200 μL
PPARGC1B-ARHGEF37-20-ORGO 20 (40 μL) 200 μL
PPARGC1B-ARHGEF37-20-ORAQ 20 (40 μL) 200 μL
PPARGC1B-ARHGEF37-20-GORE 20 (40 μL) 200 μL
PPARGC1B-ARHGEF37-20-GOOR 20 (40 μL) 200 μL
PPARGC1B-ARHGEF37-20-GOGO 20 (40 μL) 200 μL
PPARGC1B-ARHGEF37-20-GOGR 20 (40 μL) 200 μL
PPARGC1B-ARHGEF37-20-GOAQ 20 (40 μL) 200 μL
PPARGC1B-ARHGEF37-20-GRRE 20 (40 μL) 200 μL
PPARGC1B-ARHGEF37-20-GROR 20 (40 μL) 200 μL
PPARGC1B-ARHGEF37-20-GRGO 20 (40 μL) 200 μL
PPARGC1B-ARHGEF37-20-GRGR 20 (40 μL) 200 μL
PPARGC1B-ARHGEF37-20-GRAQ 20 (40 μL) 200 μL
PPARGC1B-ARHGEF37-20-AQRE 20 (40 μL) 200 μL
PPARGC1B-ARHGEF37-20-AQOR 20 (40 μL) 200 μL
PPARGC1B-ARHGEF37-20-AQGO 20 (40 μL) 200 μL
PPARGC1B-ARHGEF37-20-AQGR 20 (40 μL) 200 μL
PPARGC1B-ARHGEF37-20-AQAQ 20 (40 μL) 200 μL

PPARGC1B Gene Summary

The protein encoded by this gene stimulates the activity of several transcription factors and nuclear receptors, including estrogen receptor alpha, nuclear respiratory factor 1, and glucocorticoid receptor. The encoded protein may be involved in fat oxidation, non-oxidative glucose metabolism, and the regulation of energy expenditure. This protein is downregulated in prediabetic and type 2 diabetes mellitus patients. Certain allelic variations in this gene increase the risk of the development of obesity. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]

Gene Name: PPARG Coactivator 1 Beta

Chromosome: CHR5: 149109814 -149234585

Locus: 5q32

ARHGEF37 Gene Summary

The Rho Guanine Nucleotide Exchange Factor 37 (ARHGEF37) gene is located on chr5 :148961134-149014527 at 5q32.

Gene Name: Rho Guanine Nucleotide Exchange Factor 37

Chromosome: CHR5: 148961134 -149014527

Locus: 5q32

Gene Diseases

The PPARGC1B ARHGEF37 Fusion has been associated with the following diseases:

Disease Name
Head And Neck Squamous Cell Carcinoma 

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.