PPARG-SYN2 Fusion FISH Probe
The PPARG-SYN2 Fusion FISH Probe is used to confirm a fusion of the PPARG and SYN2 genes. The fusion of the PPARG and SYN2 genes has been associated with Bladder Urothelial Carcinoma, and Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PPARG-SYN2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PPARG-SYN2-20-RERE | 20 (40 μL) | 200 μL |
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| PPARG-SYN2-20-REOR | 20 (40 μL) | 200 μL |
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| PPARG-SYN2-20-REGO | 20 (40 μL) | 200 μL |
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| PPARG-SYN2-20-REGR | 20 (40 μL) | 200 μL |
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| PPARG-SYN2-20-REAQ | 20 (40 μL) | 200 μL |
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| PPARG-SYN2-20-ORRE | 20 (40 μL) | 200 μL |
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| PPARG-SYN2-20-OROR | 20 (40 μL) | 200 μL |
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| PPARG-SYN2-20-ORGO | 20 (40 μL) | 200 μL |
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| PPARG-SYN2-20-ORAQ | 20 (40 μL) | 200 μL |
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| PPARG-SYN2-20-GORE | 20 (40 μL) | 200 μL |
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| PPARG-SYN2-20-GOOR | 20 (40 μL) | 200 μL |
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| PPARG-SYN2-20-GOGO | 20 (40 μL) | 200 μL |
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| PPARG-SYN2-20-GOGR | 20 (40 μL) | 200 μL |
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| PPARG-SYN2-20-GOAQ | 20 (40 μL) | 200 μL |
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| PPARG-SYN2-20-GRRE | 20 (40 μL) | 200 μL |
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| PPARG-SYN2-20-GROR | 20 (40 μL) | 200 μL |
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| PPARG-SYN2-20-GRGO | 20 (40 μL) | 200 μL |
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| PPARG-SYN2-20-GRGR | 20 (40 μL) | 200 μL |
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| PPARG-SYN2-20-GRAQ | 20 (40 μL) | 200 μL |
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| PPARG-SYN2-20-AQRE | 20 (40 μL) | 200 μL |
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| PPARG-SYN2-20-AQOR | 20 (40 μL) | 200 μL |
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| PPARG-SYN2-20-AQGO | 20 (40 μL) | 200 μL |
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| PPARG-SYN2-20-AQGR | 20 (40 μL) | 200 μL |
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| PPARG-SYN2-20-AQAQ | 20 (40 μL) | 200 μL |
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PPARG Gene Summary
This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Jul 2008]
Gene Name: Peroxisome Proliferator Activated Receptor Gamma
Chromosome: CHR3: 12329348 -12475855
Locus: 3p25.2
SYN2 Gene Summary
This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family encodes a neuron-specific phosphoprotein that selectively binds to small synaptic vesicles in the presynaptic nerve terminal. Polymorphisms in this gene are associated with abnormal presynaptic function and related neuronal disorders, including autism, epilepsy, bipolar disorder and schizophrenia. Alternative splicing of this gene results in multiple transcript variants. The tissue inhibitor of metalloproteinase 4 gene is located within an intron of this gene and is transcribed in the opposite direction. [provided by RefSeq, Feb 2014]
Gene Name: Synapsin II
Chromosome: CHR3: 12045861 -12233532
Locus: 3p25.2
Gene Diseases
The PPARG SYN2 Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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