PPARG-PAX8 Fusion FISH Probe
The PPARG-PAX8 Fusion FISH Probe is used to confirm a fusion of the PPARG and PAX8 genes. The fusion of the PPARG and PAX8 genes has been associated with Thyroid Carcinoma, Thyroid Carcinoma, and Thyroid Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PPARG-PAX8-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PPARG-PAX8-20-RERE | 20 (40 μL) | 200 μL |
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| PPARG-PAX8-20-REOR | 20 (40 μL) | 200 μL |
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| PPARG-PAX8-20-REGO | 20 (40 μL) | 200 μL |
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| PPARG-PAX8-20-REGR | 20 (40 μL) | 200 μL |
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| PPARG-PAX8-20-REAQ | 20 (40 μL) | 200 μL |
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| PPARG-PAX8-20-ORRE | 20 (40 μL) | 200 μL |
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| PPARG-PAX8-20-OROR | 20 (40 μL) | 200 μL |
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| PPARG-PAX8-20-ORGO | 20 (40 μL) | 200 μL |
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| PPARG-PAX8-20-ORAQ | 20 (40 μL) | 200 μL |
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| PPARG-PAX8-20-GORE | 20 (40 μL) | 200 μL |
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| PPARG-PAX8-20-GOOR | 20 (40 μL) | 200 μL |
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| PPARG-PAX8-20-GOGO | 20 (40 μL) | 200 μL |
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| PPARG-PAX8-20-GOGR | 20 (40 μL) | 200 μL |
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| PPARG-PAX8-20-GOAQ | 20 (40 μL) | 200 μL |
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| PPARG-PAX8-20-GRRE | 20 (40 μL) | 200 μL |
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| PPARG-PAX8-20-GROR | 20 (40 μL) | 200 μL |
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| PPARG-PAX8-20-GRGO | 20 (40 μL) | 200 μL |
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| PPARG-PAX8-20-GRGR | 20 (40 μL) | 200 μL |
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| PPARG-PAX8-20-GRAQ | 20 (40 μL) | 200 μL |
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| PPARG-PAX8-20-AQRE | 20 (40 μL) | 200 μL |
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| PPARG-PAX8-20-AQOR | 20 (40 μL) | 200 μL |
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| PPARG-PAX8-20-AQGO | 20 (40 μL) | 200 μL |
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| PPARG-PAX8-20-AQGR | 20 (40 μL) | 200 μL |
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| PPARG-PAX8-20-AQAQ | 20 (40 μL) | 200 μL |
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PPARG Gene Summary
This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Jul 2008]
Gene Name: Peroxisome Proliferator Activated Receptor Gamma
Chromosome: CHR3: 12329348 -12475855
Locus: 3p25.2
PAX8 Gene Summary
This gene encodes a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Mar 2010]
Gene Name: Paired Box 8
Chromosome: CHR2: 113973573 -114036498
Locus: 2q13
Gene Diseases
The PPARG PAX8 Fusion has been associated with the following diseases:
| Disease Name |
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| Thyroid Carcinoma |
| Thyroid Carcinoma |
| Thyroid Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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