PPARA-RAB2A Fusion FISH Probe
The PPARA-RAB2A Fusion FISH Probe is used to confirm a fusion of the PPARA and RAB2A genes. The fusion of the PPARA and RAB2A genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PPARA-RAB2A-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PPARA-RAB2A-20-RERE | 20 (40 μL) | 200 μL |
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| PPARA-RAB2A-20-REOR | 20 (40 μL) | 200 μL |
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| PPARA-RAB2A-20-REGO | 20 (40 μL) | 200 μL |
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| PPARA-RAB2A-20-REGR | 20 (40 μL) | 200 μL |
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| PPARA-RAB2A-20-REAQ | 20 (40 μL) | 200 μL |
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| PPARA-RAB2A-20-ORRE | 20 (40 μL) | 200 μL |
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| PPARA-RAB2A-20-OROR | 20 (40 μL) | 200 μL |
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| PPARA-RAB2A-20-ORGO | 20 (40 μL) | 200 μL |
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| PPARA-RAB2A-20-ORAQ | 20 (40 μL) | 200 μL |
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| PPARA-RAB2A-20-GORE | 20 (40 μL) | 200 μL |
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| PPARA-RAB2A-20-GOOR | 20 (40 μL) | 200 μL |
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| PPARA-RAB2A-20-GOGO | 20 (40 μL) | 200 μL |
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| PPARA-RAB2A-20-GOGR | 20 (40 μL) | 200 μL |
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| PPARA-RAB2A-20-GOAQ | 20 (40 μL) | 200 μL |
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| PPARA-RAB2A-20-GRRE | 20 (40 μL) | 200 μL |
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| PPARA-RAB2A-20-GROR | 20 (40 μL) | 200 μL |
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| PPARA-RAB2A-20-GRGO | 20 (40 μL) | 200 μL |
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| PPARA-RAB2A-20-GRGR | 20 (40 μL) | 200 μL |
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| PPARA-RAB2A-20-GRAQ | 20 (40 μL) | 200 μL |
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| PPARA-RAB2A-20-AQRE | 20 (40 μL) | 200 μL |
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| PPARA-RAB2A-20-AQOR | 20 (40 μL) | 200 μL |
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| PPARA-RAB2A-20-AQGO | 20 (40 μL) | 200 μL |
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| PPARA-RAB2A-20-AQGR | 20 (40 μL) | 200 μL |
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| PPARA-RAB2A-20-AQAQ | 20 (40 μL) | 200 μL |
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PPARA Gene Summary
Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers; this term arises because they induce an increase in the size and number of peroxisomes. Peroxisomes are subcellular organelles found in plants and animals that contain enzymes for respiration and for cholesterol and lipid metabolism. The action of peroxisome proliferators is thought to be mediated via specific receptors, called PPARs, which belong to the steroid hormone receptor superfamily. PPARs affect the expression of target genes involved in cell proliferation, cell differentiation and in immune and inflammation responses. Three closely related subtypes (alpha, beta/delta, and gamma) have been identified. This gene encodes the subtype PPAR-alpha, which is a nuclear transcription factor. Multiple alternatively spliced transcript variants have been described for this gene, although the full-length nature of only two has been determined. [provided by RefSeq, Jul 2008]
Gene Name: Peroxisome Proliferator Activated Receptor Alpha
Chromosome: CHR22: 46546498 -46639653
Locus: 22q13.31
RAB2A Gene Summary
The protein encoded by this gene belongs to the Rab family, members of which are small molecular weight guanosine triphosphatases (GTPases) that contain highly conserved domains involved in GTP binding and hydrolysis. The Rabs are membrane-bound proteins, involved in vesicular fusion and trafficking. This protein is a resident of pre-Golgi intermediates, and is required for protein transport from the endoplasmic reticulum (ER) to the Golgi complex. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Gene Name: RAB2A, Member RAS Oncogene Family
Chromosome: CHR8: 61429468 -61536203
Locus: 8q12.1-q12.2
Gene Diseases
The PPARA RAB2A Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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