PPAP2A-MLPH Fusion FISH Probe
The PPAP2A-MLPH Fusion FISH Probe is used to confirm a fusion of the PPAP2A and MLPH genes. The fusion of the PPAP2A and MLPH genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PPAP2A-MLPH-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PPAP2A-MLPH-20-RERE | 20 (40 μL) | 200 μL |
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| PPAP2A-MLPH-20-REOR | 20 (40 μL) | 200 μL |
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| PPAP2A-MLPH-20-REGO | 20 (40 μL) | 200 μL |
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| PPAP2A-MLPH-20-REGR | 20 (40 μL) | 200 μL |
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| PPAP2A-MLPH-20-REAQ | 20 (40 μL) | 200 μL |
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| PPAP2A-MLPH-20-ORRE | 20 (40 μL) | 200 μL |
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| PPAP2A-MLPH-20-OROR | 20 (40 μL) | 200 μL |
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| PPAP2A-MLPH-20-ORGO | 20 (40 μL) | 200 μL |
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| PPAP2A-MLPH-20-ORAQ | 20 (40 μL) | 200 μL |
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| PPAP2A-MLPH-20-GORE | 20 (40 μL) | 200 μL |
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| PPAP2A-MLPH-20-GOOR | 20 (40 μL) | 200 μL |
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| PPAP2A-MLPH-20-GOGO | 20 (40 μL) | 200 μL |
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| PPAP2A-MLPH-20-GOGR | 20 (40 μL) | 200 μL |
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| PPAP2A-MLPH-20-GOAQ | 20 (40 μL) | 200 μL |
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| PPAP2A-MLPH-20-GRRE | 20 (40 μL) | 200 μL |
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| PPAP2A-MLPH-20-GROR | 20 (40 μL) | 200 μL |
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| PPAP2A-MLPH-20-GRGO | 20 (40 μL) | 200 μL |
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| PPAP2A-MLPH-20-GRGR | 20 (40 μL) | 200 μL |
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| PPAP2A-MLPH-20-GRAQ | 20 (40 μL) | 200 μL |
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| PPAP2A-MLPH-20-AQRE | 20 (40 μL) | 200 μL |
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| PPAP2A-MLPH-20-AQOR | 20 (40 μL) | 200 μL |
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| PPAP2A-MLPH-20-AQGO | 20 (40 μL) | 200 μL |
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| PPAP2A-MLPH-20-AQGR | 20 (40 μL) | 200 μL |
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| PPAP2A-MLPH-20-AQAQ | 20 (40 μL) | 200 μL |
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MLPH Gene Summary
This gene encodes a member of the exophilin subfamily of Rab effector proteins. The protein forms a ternary complex with the small Ras-related GTPase Rab27A in its GTP-bound form and the motor protein myosin Va. A similar protein complex in mouse functions to tether pigment-producing organelles called melanosomes to the actin cytoskeleton in melanocytes, and is required for visible pigmentation in the hair and skin. A mutation in this gene results in Griscelli syndrome type 3, which is characterized by a silver-gray hair color and abnormal pigment distribution in the hair shaft. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2013]
Gene Name: Melanophilin
Chromosome: CHR2: 238395877 -238463961
Locus: 2q37.3
Gene Diseases
The PPAP2A MLPH Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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