POU2F1-CD247 Fusion FISH Probe
The POU2F1-CD247 Fusion FISH Probe is used to confirm a fusion of the POU2F1 and CD247 genes. The fusion of the POU2F1 and CD247 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| POU2F1-CD247-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| POU2F1-CD247-20-RERE | 20 (40 μL) | 200 μL |
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| POU2F1-CD247-20-REOR | 20 (40 μL) | 200 μL |
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| POU2F1-CD247-20-REGO | 20 (40 μL) | 200 μL |
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| POU2F1-CD247-20-REGR | 20 (40 μL) | 200 μL |
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| POU2F1-CD247-20-REAQ | 20 (40 μL) | 200 μL |
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| POU2F1-CD247-20-ORRE | 20 (40 μL) | 200 μL |
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| POU2F1-CD247-20-OROR | 20 (40 μL) | 200 μL |
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| POU2F1-CD247-20-ORGO | 20 (40 μL) | 200 μL |
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| POU2F1-CD247-20-ORAQ | 20 (40 μL) | 200 μL |
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| POU2F1-CD247-20-GORE | 20 (40 μL) | 200 μL |
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| POU2F1-CD247-20-GOOR | 20 (40 μL) | 200 μL |
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| POU2F1-CD247-20-GOGO | 20 (40 μL) | 200 μL |
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| POU2F1-CD247-20-GOGR | 20 (40 μL) | 200 μL |
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| POU2F1-CD247-20-GOAQ | 20 (40 μL) | 200 μL |
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| POU2F1-CD247-20-GRRE | 20 (40 μL) | 200 μL |
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| POU2F1-CD247-20-GROR | 20 (40 μL) | 200 μL |
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| POU2F1-CD247-20-GRGO | 20 (40 μL) | 200 μL |
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| POU2F1-CD247-20-GRGR | 20 (40 μL) | 200 μL |
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| POU2F1-CD247-20-GRAQ | 20 (40 μL) | 200 μL |
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| POU2F1-CD247-20-AQRE | 20 (40 μL) | 200 μL |
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| POU2F1-CD247-20-AQOR | 20 (40 μL) | 200 μL |
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| POU2F1-CD247-20-AQGO | 20 (40 μL) | 200 μL |
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| POU2F1-CD247-20-AQGR | 20 (40 μL) | 200 μL |
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| POU2F1-CD247-20-AQAQ | 20 (40 μL) | 200 μL |
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CD247 Gene Summary
The protein encoded by this gene is T-cell receptor zeta, which together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: CD247 Molecule
Chromosome: CHR1: 167399876 -167487847
Locus: 1q24.2
POU2F1 Gene Summary
The OCT1 transcription factor was among the first identified members of the POU transcription factor family (summarized by Sturm et al., 1993 [PubMed 8314572]). Members of this family contain the POU domain, a 160-amino acid region necessary for DNA binding to the octameric sequence ATGCAAAT.[supplied by OMIM, Jul 2010]
Gene Name: POU Class 2 Homeobox 1
Chromosome: CHR1: 167190065 -167396582
Locus: 1q24.2
Gene Diseases
The POU2F1 CD247 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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