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POU2F1-CD247 Fusion FISH Probe

The POU2F1-CD247 Fusion FISH Probe is used to confirm a fusion of the POU2F1 and CD247 genes. The fusion of the POU2F1 and CD247 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
POU2F1-CD247-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
POU2F1-CD247-20-RERE 20 (40 μL) 200 μL
POU2F1-CD247-20-REOR 20 (40 μL) 200 μL
POU2F1-CD247-20-REGO 20 (40 μL) 200 μL
POU2F1-CD247-20-REGR 20 (40 μL) 200 μL
POU2F1-CD247-20-REAQ 20 (40 μL) 200 μL
POU2F1-CD247-20-ORRE 20 (40 μL) 200 μL
POU2F1-CD247-20-OROR 20 (40 μL) 200 μL
POU2F1-CD247-20-ORGO 20 (40 μL) 200 μL
POU2F1-CD247-20-ORAQ 20 (40 μL) 200 μL
POU2F1-CD247-20-GORE 20 (40 μL) 200 μL
POU2F1-CD247-20-GOOR 20 (40 μL) 200 μL
POU2F1-CD247-20-GOGO 20 (40 μL) 200 μL
POU2F1-CD247-20-GOGR 20 (40 μL) 200 μL
POU2F1-CD247-20-GOAQ 20 (40 μL) 200 μL
POU2F1-CD247-20-GRRE 20 (40 μL) 200 μL
POU2F1-CD247-20-GROR 20 (40 μL) 200 μL
POU2F1-CD247-20-GRGO 20 (40 μL) 200 μL
POU2F1-CD247-20-GRGR 20 (40 μL) 200 μL
POU2F1-CD247-20-GRAQ 20 (40 μL) 200 μL
POU2F1-CD247-20-AQRE 20 (40 μL) 200 μL
POU2F1-CD247-20-AQOR 20 (40 μL) 200 μL
POU2F1-CD247-20-AQGO 20 (40 μL) 200 μL
POU2F1-CD247-20-AQGR 20 (40 μL) 200 μL
POU2F1-CD247-20-AQAQ 20 (40 μL) 200 μL

CD247 Gene Summary

The protein encoded by this gene is T-cell receptor zeta, which together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Gene Name: CD247 Molecule

Chromosome: CHR1: 167399876 -167487847

Locus: 1q24.2

POU2F1 Gene Summary

The OCT1 transcription factor was among the first identified members of the POU transcription factor family (summarized by Sturm et al., 1993 [PubMed 8314572]). Members of this family contain the POU domain, a 160-amino acid region necessary for DNA binding to the octameric sequence ATGCAAAT.[supplied by OMIM, Jul 2010]

Gene Name: POU Class 2 Homeobox 1

Chromosome: CHR1: 167190065 -167396582

Locus: 1q24.2

Gene Diseases

The POU2F1 CD247 Fusion has been associated with the following diseases:

Disease Name
Breast Invasive Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.