POT1-RTKN2 Fusion FISH Probe
The POT1-RTKN2 Fusion FISH Probe is used to confirm a fusion of the POT1 and RTKN2 genes. The fusion of the POT1 and RTKN2 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| POT1-RTKN2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| POT1-RTKN2-20-RERE | 20 (40 μL) | 200 μL |
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| POT1-RTKN2-20-REOR | 20 (40 μL) | 200 μL |
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| POT1-RTKN2-20-REGO | 20 (40 μL) | 200 μL |
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| POT1-RTKN2-20-REGR | 20 (40 μL) | 200 μL |
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| POT1-RTKN2-20-REAQ | 20 (40 μL) | 200 μL |
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| POT1-RTKN2-20-ORRE | 20 (40 μL) | 200 μL |
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| POT1-RTKN2-20-OROR | 20 (40 μL) | 200 μL |
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| POT1-RTKN2-20-ORGO | 20 (40 μL) | 200 μL |
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| POT1-RTKN2-20-ORAQ | 20 (40 μL) | 200 μL |
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| POT1-RTKN2-20-GORE | 20 (40 μL) | 200 μL |
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| POT1-RTKN2-20-GOOR | 20 (40 μL) | 200 μL |
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| POT1-RTKN2-20-GOGO | 20 (40 μL) | 200 μL |
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| POT1-RTKN2-20-GOGR | 20 (40 μL) | 200 μL |
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| POT1-RTKN2-20-GOAQ | 20 (40 μL) | 200 μL |
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| POT1-RTKN2-20-GRRE | 20 (40 μL) | 200 μL |
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| POT1-RTKN2-20-GROR | 20 (40 μL) | 200 μL |
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| POT1-RTKN2-20-GRGO | 20 (40 μL) | 200 μL |
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| POT1-RTKN2-20-GRGR | 20 (40 μL) | 200 μL |
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| POT1-RTKN2-20-GRAQ | 20 (40 μL) | 200 μL |
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| POT1-RTKN2-20-AQRE | 20 (40 μL) | 200 μL |
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| POT1-RTKN2-20-AQOR | 20 (40 μL) | 200 μL |
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| POT1-RTKN2-20-AQGO | 20 (40 μL) | 200 μL |
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| POT1-RTKN2-20-AQGR | 20 (40 μL) | 200 μL |
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| POT1-RTKN2-20-AQAQ | 20 (40 μL) | 200 μL |
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POT1 Gene Summary
This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008]
Gene Name: Protection Of Telomeres 1
Chromosome: CHR7: 124462439 -124570037
Locus: 7q31.33
RTKN2 Gene Summary
The Rhotekin 2 (RTKN2) gene is located on chr10 :63952952-64028466 at 10q21.2.
Gene Name: Rhotekin 2
Chromosome: CHR10: 63952952 -64028466
Locus: 10q21.2
Gene Diseases
The POT1 RTKN2 Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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