POR-RHBDD2 Fusion FISH Probe
The POR-RHBDD2 Fusion FISH Probe is used to confirm a fusion of the POR and RHBDD2 genes. The fusion of the POR and RHBDD2 genes has been associated with Esophageal Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| POR-RHBDD2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| POR-RHBDD2-20-RERE | 20 (40 μL) | 200 μL |
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| POR-RHBDD2-20-REOR | 20 (40 μL) | 200 μL |
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| POR-RHBDD2-20-REGO | 20 (40 μL) | 200 μL |
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| POR-RHBDD2-20-REGR | 20 (40 μL) | 200 μL |
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| POR-RHBDD2-20-REAQ | 20 (40 μL) | 200 μL |
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| POR-RHBDD2-20-ORRE | 20 (40 μL) | 200 μL |
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| POR-RHBDD2-20-OROR | 20 (40 μL) | 200 μL |
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| POR-RHBDD2-20-ORGO | 20 (40 μL) | 200 μL |
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| POR-RHBDD2-20-ORAQ | 20 (40 μL) | 200 μL |
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| POR-RHBDD2-20-GORE | 20 (40 μL) | 200 μL |
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| POR-RHBDD2-20-GOOR | 20 (40 μL) | 200 μL |
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| POR-RHBDD2-20-GOGO | 20 (40 μL) | 200 μL |
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| POR-RHBDD2-20-GOGR | 20 (40 μL) | 200 μL |
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| POR-RHBDD2-20-GOAQ | 20 (40 μL) | 200 μL |
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| POR-RHBDD2-20-GRRE | 20 (40 μL) | 200 μL |
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| POR-RHBDD2-20-GROR | 20 (40 μL) | 200 μL |
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| POR-RHBDD2-20-GRGO | 20 (40 μL) | 200 μL |
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| POR-RHBDD2-20-GRGR | 20 (40 μL) | 200 μL |
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| POR-RHBDD2-20-GRAQ | 20 (40 μL) | 200 μL |
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| POR-RHBDD2-20-AQRE | 20 (40 μL) | 200 μL |
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| POR-RHBDD2-20-AQOR | 20 (40 μL) | 200 μL |
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| POR-RHBDD2-20-AQGO | 20 (40 μL) | 200 μL |
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| POR-RHBDD2-20-AQGR | 20 (40 μL) | 200 μL |
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| POR-RHBDD2-20-AQAQ | 20 (40 μL) | 200 μL |
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POR Gene Summary
This gene encodes an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome. [provided by RefSeq, Jul 2008]
Gene Name: Cytochrome P450 Oxidoreductase
Chromosome: CHR7: 75544419 -75616173
Locus: 7q11.23
RHBDD2 Gene Summary
The protein encoded by this gene is a member of the rhomboid family of membrane-bound proteases and is overexpressed in some breast cancers. Members of this family are involved in intramembrane proteolysis. In mouse, the orthologous protein associates with the Golgi body. [provided by RefSeq, Sep 2016]
Gene Name: Rhomboid Domain Containing 2
Chromosome: CHR7: 75508316 -75518244
Locus: 7q11.23
Gene Diseases
The POR RHBDD2 Fusion has been associated with the following diseases:
| Disease Name |
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| Esophageal Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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