POLK-SKIV2L2 Fusion FISH Probe
The POLK-SKIV2L2 Fusion FISH Probe is used to confirm a fusion of the POLK and SKIV2L2 genes. The fusion of the POLK and SKIV2L2 genes has been associated with Rectum Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| POLK-SKIV2L2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| POLK-SKIV2L2-20-RERE | 20 (40 μL) | 200 μL |
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| POLK-SKIV2L2-20-REOR | 20 (40 μL) | 200 μL |
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| POLK-SKIV2L2-20-REGO | 20 (40 μL) | 200 μL |
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| POLK-SKIV2L2-20-REGR | 20 (40 μL) | 200 μL |
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| POLK-SKIV2L2-20-REAQ | 20 (40 μL) | 200 μL |
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| POLK-SKIV2L2-20-ORRE | 20 (40 μL) | 200 μL |
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| POLK-SKIV2L2-20-OROR | 20 (40 μL) | 200 μL |
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| POLK-SKIV2L2-20-ORGO | 20 (40 μL) | 200 μL |
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| POLK-SKIV2L2-20-ORAQ | 20 (40 μL) | 200 μL |
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| POLK-SKIV2L2-20-GORE | 20 (40 μL) | 200 μL |
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| POLK-SKIV2L2-20-GOOR | 20 (40 μL) | 200 μL |
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| POLK-SKIV2L2-20-GOGO | 20 (40 μL) | 200 μL |
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| POLK-SKIV2L2-20-GOGR | 20 (40 μL) | 200 μL |
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| POLK-SKIV2L2-20-GOAQ | 20 (40 μL) | 200 μL |
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| POLK-SKIV2L2-20-GRRE | 20 (40 μL) | 200 μL |
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| POLK-SKIV2L2-20-GROR | 20 (40 μL) | 200 μL |
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| POLK-SKIV2L2-20-GRGO | 20 (40 μL) | 200 μL |
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| POLK-SKIV2L2-20-GRGR | 20 (40 μL) | 200 μL |
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| POLK-SKIV2L2-20-GRAQ | 20 (40 μL) | 200 μL |
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| POLK-SKIV2L2-20-AQRE | 20 (40 μL) | 200 μL |
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| POLK-SKIV2L2-20-AQOR | 20 (40 μL) | 200 μL |
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| POLK-SKIV2L2-20-AQGO | 20 (40 μL) | 200 μL |
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| POLK-SKIV2L2-20-AQGR | 20 (40 μL) | 200 μL |
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| POLK-SKIV2L2-20-AQAQ | 20 (40 μL) | 200 μL |
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SKIV2L2 Gene Summary
The Ski2 Like RNA Helicase 2 (SKIV2L2) gene is located on chr5 :54603575-54721409 at 5q11.2.
Gene Name: Ski2 Like RNA Helicase 2
Chromosome: CHR5: 54603575 -54721409
Locus: 5q11.2
POLK Gene Summary
This gene encodes a member of the DNA polymerase type-Y family of proteins. The encoded protein is a specialized DNA polymerase that catalyzes translesion DNA synthesis, which allows DNA replication in the presence of DNA lesions. Human cell lines lacking a functional copy of this gene exhibit impaired genome integrity and enhanced susceptibility to oxidative damage. Mutations in this gene that impair enzyme activity may be associated with prostate cancer in human patients. [provided by RefSeq, Sep 2016]
Gene Name: DNA Polymerase Kappa
Chromosome: CHR5: 74807656 -74895646
Locus: 5q13.3
Gene Diseases
The POLK SKIV2L2 Fusion has been associated with the following diseases:
| Disease Name |
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| Rectum Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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