POC1A-TWF2 Fusion FISH Probe
The POC1A-TWF2 Fusion FISH Probe is used to confirm a fusion of the POC1A and TWF2 genes. The fusion of the POC1A and TWF2 genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| POC1A-TWF2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| POC1A-TWF2-20-RERE | 20 (40 μL) | 200 μL |
|
|
| POC1A-TWF2-20-REOR | 20 (40 μL) | 200 μL |
|
|
| POC1A-TWF2-20-REGO | 20 (40 μL) | 200 μL |
|
|
| POC1A-TWF2-20-REGR | 20 (40 μL) | 200 μL |
|
|
| POC1A-TWF2-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| POC1A-TWF2-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| POC1A-TWF2-20-OROR | 20 (40 μL) | 200 μL |
|
|
| POC1A-TWF2-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| POC1A-TWF2-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| POC1A-TWF2-20-GORE | 20 (40 μL) | 200 μL |
|
|
| POC1A-TWF2-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| POC1A-TWF2-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| POC1A-TWF2-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| POC1A-TWF2-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| POC1A-TWF2-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| POC1A-TWF2-20-GROR | 20 (40 μL) | 200 μL |
|
|
| POC1A-TWF2-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| POC1A-TWF2-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| POC1A-TWF2-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| POC1A-TWF2-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| POC1A-TWF2-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| POC1A-TWF2-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| POC1A-TWF2-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| POC1A-TWF2-20-AQAQ | 20 (40 μL) | 200 μL |
|
TWF2 Gene Summary
The protein encoded by this gene was identified by its interaction with the catalytic domain of protein kinase C-zeta. The encoded protein contains an actin-binding site and an ATP-binding site. It is most closely related to twinfilin (PTK9), a conserved actin monomer-binding protein. [provided by RefSeq, Jul 2008]
Gene Name: Twinfilin Actin Binding Protein 2
Chromosome: CHR3: 52262625 -52273183
Locus: 3p21.2
POC1A Gene Summary
POC1 proteins contain an N-terminal WD40 domain and a C-terminal coiled coil domain and are part of centrosomes. They play an important role in basal body and cilia formation. This gene encodes one of the two POC1 proteins found in humans. Mutations in this gene result in short stature, onychodysplasia, facial dysmorphism, and hypotrichosis (SOFT) syndrome. [provided by RefSeq, Sep 2012]
Gene Name: POC1 Centriolar Protein A
Chromosome: CHR3: 52109248 -52188706
Locus: 3p21.2
Gene Diseases
The POC1A TWF2 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|