PLXNB2-TMPRSS6 Fusion FISH Probe
The PLXNB2-TMPRSS6 Fusion FISH Probe is used to confirm a fusion of the PLXNB2 and TMPRSS6 genes. The fusion of the PLXNB2 and TMPRSS6 genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PLXNB2-TMPRSS6-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PLXNB2-TMPRSS6-20-RERE | 20 (40 μL) | 200 μL |
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| PLXNB2-TMPRSS6-20-REOR | 20 (40 μL) | 200 μL |
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| PLXNB2-TMPRSS6-20-REGO | 20 (40 μL) | 200 μL |
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| PLXNB2-TMPRSS6-20-REGR | 20 (40 μL) | 200 μL |
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| PLXNB2-TMPRSS6-20-REAQ | 20 (40 μL) | 200 μL |
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| PLXNB2-TMPRSS6-20-ORRE | 20 (40 μL) | 200 μL |
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| PLXNB2-TMPRSS6-20-OROR | 20 (40 μL) | 200 μL |
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| PLXNB2-TMPRSS6-20-ORGO | 20 (40 μL) | 200 μL |
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| PLXNB2-TMPRSS6-20-ORAQ | 20 (40 μL) | 200 μL |
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| PLXNB2-TMPRSS6-20-GORE | 20 (40 μL) | 200 μL |
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| PLXNB2-TMPRSS6-20-GOOR | 20 (40 μL) | 200 μL |
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| PLXNB2-TMPRSS6-20-GOGO | 20 (40 μL) | 200 μL |
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| PLXNB2-TMPRSS6-20-GOGR | 20 (40 μL) | 200 μL |
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| PLXNB2-TMPRSS6-20-GOAQ | 20 (40 μL) | 200 μL |
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| PLXNB2-TMPRSS6-20-GRRE | 20 (40 μL) | 200 μL |
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| PLXNB2-TMPRSS6-20-GROR | 20 (40 μL) | 200 μL |
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| PLXNB2-TMPRSS6-20-GRGO | 20 (40 μL) | 200 μL |
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| PLXNB2-TMPRSS6-20-GRGR | 20 (40 μL) | 200 μL |
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| PLXNB2-TMPRSS6-20-GRAQ | 20 (40 μL) | 200 μL |
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| PLXNB2-TMPRSS6-20-AQRE | 20 (40 μL) | 200 μL |
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| PLXNB2-TMPRSS6-20-AQOR | 20 (40 μL) | 200 μL |
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| PLXNB2-TMPRSS6-20-AQGO | 20 (40 μL) | 200 μL |
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| PLXNB2-TMPRSS6-20-AQGR | 20 (40 μL) | 200 μL |
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| PLXNB2-TMPRSS6-20-AQAQ | 20 (40 μL) | 200 μL |
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PLXNB2 Gene Summary
Members of the B class of plexins, such as PLXNB2 are transmembrane receptors that participate in axon guidance and cell migration in response to semaphorins (Perrot et al. (2002) [PubMed 12183458]).[supplied by OMIM, Mar 2008]
Gene Name: Plexin B2
Chromosome: CHR22: 50713407 -50746001
Locus: 22q13.33
TMPRSS6 Gene Summary
The protein encoded by this gene is a type II transmembrane serine proteinase that is found attached to the cell surface. The encoded protein may be involved in matrix remodeling processes in the liver. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
Gene Name: Transmembrane Protease, Serine 6
Chromosome: CHR22: 37461478 -37499693
Locus: 22q12.3
Gene Diseases
The PLXNB2 TMPRSS6 Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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