PLXNA3-ATP6AP1 Fusion FISH Probe
The PLXNA3-ATP6AP1 Fusion FISH Probe is used to confirm a fusion of the PLXNA3 and ATP6AP1 genes. The fusion of the PLXNA3 and ATP6AP1 genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PLXNA3-ATP6AP1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PLXNA3-ATP6AP1-20-RERE | 20 (40 μL) | 200 μL |
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| PLXNA3-ATP6AP1-20-REOR | 20 (40 μL) | 200 μL |
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| PLXNA3-ATP6AP1-20-REGO | 20 (40 μL) | 200 μL |
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| PLXNA3-ATP6AP1-20-REGR | 20 (40 μL) | 200 μL |
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| PLXNA3-ATP6AP1-20-REAQ | 20 (40 μL) | 200 μL |
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| PLXNA3-ATP6AP1-20-ORRE | 20 (40 μL) | 200 μL |
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| PLXNA3-ATP6AP1-20-OROR | 20 (40 μL) | 200 μL |
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| PLXNA3-ATP6AP1-20-ORGO | 20 (40 μL) | 200 μL |
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| PLXNA3-ATP6AP1-20-ORAQ | 20 (40 μL) | 200 μL |
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| PLXNA3-ATP6AP1-20-GORE | 20 (40 μL) | 200 μL |
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| PLXNA3-ATP6AP1-20-GOOR | 20 (40 μL) | 200 μL |
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| PLXNA3-ATP6AP1-20-GOGO | 20 (40 μL) | 200 μL |
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| PLXNA3-ATP6AP1-20-GOGR | 20 (40 μL) | 200 μL |
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| PLXNA3-ATP6AP1-20-GOAQ | 20 (40 μL) | 200 μL |
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| PLXNA3-ATP6AP1-20-GRRE | 20 (40 μL) | 200 μL |
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| PLXNA3-ATP6AP1-20-GROR | 20 (40 μL) | 200 μL |
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| PLXNA3-ATP6AP1-20-GRGO | 20 (40 μL) | 200 μL |
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| PLXNA3-ATP6AP1-20-GRGR | 20 (40 μL) | 200 μL |
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| PLXNA3-ATP6AP1-20-GRAQ | 20 (40 μL) | 200 μL |
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| PLXNA3-ATP6AP1-20-AQRE | 20 (40 μL) | 200 μL |
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| PLXNA3-ATP6AP1-20-AQOR | 20 (40 μL) | 200 μL |
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| PLXNA3-ATP6AP1-20-AQGO | 20 (40 μL) | 200 μL |
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| PLXNA3-ATP6AP1-20-AQGR | 20 (40 μL) | 200 μL |
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| PLXNA3-ATP6AP1-20-AQAQ | 20 (40 μL) | 200 μL |
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ATP6AP1 Gene Summary
This gene encodes a component of a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. Vacuolar ATPase (V-ATPase) is comprised of a cytosolic V1 (site of the ATP catalytic site) and a transmembrane V0 domain. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, and receptor-mediated endocytosis. The encoded protein of this gene may assist in the V-ATPase-mediated acidification of neuroendocrine secretory granules. This protein may also play a role in early development. [provided by RefSeq, Aug 2013]
Gene Name: ATPase H+ Transporting Accessory Protein 1
Chromosome: CHRX: 153656977 -153664862
Locus: Xq28
PLXNA3 Gene Summary
This gene encodes a member of the plexin class of proteins. The encoded protein is a class 3 semaphorin receptor, and may be involved in cytoskeletal remodeling and as well as apoptosis. Studies of a similar gene in zebrafish suggest that it is important for axon pathfinding in the developing nervous system. This gene may be associated with tumor progression. [provided by RefSeq, Aug 2013]
Gene Name: Plexin A3
Chromosome: CHRX: 153686622 -153701985
Locus: Xq28
Gene Diseases
The PLXNA3 ATP6AP1 Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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