PLXDC1-ACE Fusion FISH Probe
The PLXDC1-ACE Fusion FISH Probe is used to confirm a fusion of the PLXDC1 and ACE genes. The fusion of the PLXDC1 and ACE genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PLXDC1-ACE-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PLXDC1-ACE-20-RERE | 20 (40 μL) | 200 μL |
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| PLXDC1-ACE-20-REOR | 20 (40 μL) | 200 μL |
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| PLXDC1-ACE-20-REGO | 20 (40 μL) | 200 μL |
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| PLXDC1-ACE-20-REGR | 20 (40 μL) | 200 μL |
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| PLXDC1-ACE-20-REAQ | 20 (40 μL) | 200 μL |
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| PLXDC1-ACE-20-ORRE | 20 (40 μL) | 200 μL |
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| PLXDC1-ACE-20-OROR | 20 (40 μL) | 200 μL |
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| PLXDC1-ACE-20-ORGO | 20 (40 μL) | 200 μL |
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| PLXDC1-ACE-20-ORAQ | 20 (40 μL) | 200 μL |
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| PLXDC1-ACE-20-GORE | 20 (40 μL) | 200 μL |
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| PLXDC1-ACE-20-GOOR | 20 (40 μL) | 200 μL |
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| PLXDC1-ACE-20-GOGO | 20 (40 μL) | 200 μL |
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| PLXDC1-ACE-20-GOGR | 20 (40 μL) | 200 μL |
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| PLXDC1-ACE-20-GOAQ | 20 (40 μL) | 200 μL |
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| PLXDC1-ACE-20-GRRE | 20 (40 μL) | 200 μL |
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| PLXDC1-ACE-20-GROR | 20 (40 μL) | 200 μL |
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| PLXDC1-ACE-20-GRGO | 20 (40 μL) | 200 μL |
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| PLXDC1-ACE-20-GRGR | 20 (40 μL) | 200 μL |
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| PLXDC1-ACE-20-GRAQ | 20 (40 μL) | 200 μL |
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| PLXDC1-ACE-20-AQRE | 20 (40 μL) | 200 μL |
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| PLXDC1-ACE-20-AQOR | 20 (40 μL) | 200 μL |
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| PLXDC1-ACE-20-AQGO | 20 (40 μL) | 200 μL |
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| PLXDC1-ACE-20-AQGR | 20 (40 μL) | 200 μL |
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| PLXDC1-ACE-20-AQAQ | 20 (40 μL) | 200 μL |
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ACE Gene Summary
This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, and two most abundant spliced variants encode the somatic form and the testicular form, respectively, that are equally active. [provided by RefSeq, May 2010]
Gene Name: Angiotensin I Converting Enzyme
Chromosome: CHR17: 61554421 -61575741
Locus: 17q23.3
PLXDC1 Gene Summary
The Plexin Domain Containing 1 (PLXDC1) gene is located on chr17 :37219555-37307902 at 17q12.
Gene Name: Plexin Domain Containing 1
Chromosome: CHR17: 37219555 -37307902
Locus: 17q12
Gene Diseases
The PLXDC1 ACE Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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