PLEKHA7-TRIM21 Fusion FISH Probe
The PLEKHA7-TRIM21 Fusion FISH Probe is used to confirm a fusion of the PLEKHA7 and TRIM21 genes. The fusion of the PLEKHA7 and TRIM21 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PLEKHA7-TRIM21-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PLEKHA7-TRIM21-20-RERE | 20 (40 μL) | 200 μL |
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| PLEKHA7-TRIM21-20-REOR | 20 (40 μL) | 200 μL |
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| PLEKHA7-TRIM21-20-REGO | 20 (40 μL) | 200 μL |
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| PLEKHA7-TRIM21-20-REGR | 20 (40 μL) | 200 μL |
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| PLEKHA7-TRIM21-20-REAQ | 20 (40 μL) | 200 μL |
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| PLEKHA7-TRIM21-20-ORRE | 20 (40 μL) | 200 μL |
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| PLEKHA7-TRIM21-20-OROR | 20 (40 μL) | 200 μL |
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| PLEKHA7-TRIM21-20-ORGO | 20 (40 μL) | 200 μL |
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| PLEKHA7-TRIM21-20-ORAQ | 20 (40 μL) | 200 μL |
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| PLEKHA7-TRIM21-20-GORE | 20 (40 μL) | 200 μL |
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| PLEKHA7-TRIM21-20-GOOR | 20 (40 μL) | 200 μL |
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| PLEKHA7-TRIM21-20-GOGO | 20 (40 μL) | 200 μL |
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| PLEKHA7-TRIM21-20-GOGR | 20 (40 μL) | 200 μL |
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| PLEKHA7-TRIM21-20-GOAQ | 20 (40 μL) | 200 μL |
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| PLEKHA7-TRIM21-20-GRRE | 20 (40 μL) | 200 μL |
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| PLEKHA7-TRIM21-20-GROR | 20 (40 μL) | 200 μL |
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| PLEKHA7-TRIM21-20-GRGO | 20 (40 μL) | 200 μL |
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| PLEKHA7-TRIM21-20-GRGR | 20 (40 μL) | 200 μL |
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| PLEKHA7-TRIM21-20-GRAQ | 20 (40 μL) | 200 μL |
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| PLEKHA7-TRIM21-20-AQRE | 20 (40 μL) | 200 μL |
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| PLEKHA7-TRIM21-20-AQOR | 20 (40 μL) | 200 μL |
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| PLEKHA7-TRIM21-20-AQGO | 20 (40 μL) | 200 μL |
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| PLEKHA7-TRIM21-20-AQGR | 20 (40 μL) | 200 μL |
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| PLEKHA7-TRIM21-20-AQAQ | 20 (40 μL) | 200 μL |
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TRIM21 Gene Summary
This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The encoded protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Alternatively spliced transcript variants for this gene have been described but the full-length nature of only one has been determined. [provided by RefSeq, Jul 2008]
Gene Name: Tripartite Motif Containing 21
Chromosome: CHR11: 4406126 -4414926
Locus: 11p15.4
PLEKHA7 Gene Summary
The Pleckstrin Homology Domain Containing A7 (PLEKHA7) gene is located on chr11 :16809206-17035963 at 11p15.2-p15.1.
Gene Name: Pleckstrin Homology Domain Containing A7
Chromosome: CHR11: 16809206 -17035963
Locus: 11p15.2-p15.1
Gene Diseases
The PLEKHA7 TRIM21 Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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