PLEKHA7-SMPD1 Fusion FISH Probe
The PLEKHA7-SMPD1 Fusion FISH Probe is used to confirm a fusion of the PLEKHA7 and SMPD1 genes. The fusion of the PLEKHA7 and SMPD1 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PLEKHA7-SMPD1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PLEKHA7-SMPD1-20-RERE | 20 (40 μL) | 200 μL |
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| PLEKHA7-SMPD1-20-REOR | 20 (40 μL) | 200 μL |
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| PLEKHA7-SMPD1-20-REGO | 20 (40 μL) | 200 μL |
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| PLEKHA7-SMPD1-20-REGR | 20 (40 μL) | 200 μL |
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| PLEKHA7-SMPD1-20-REAQ | 20 (40 μL) | 200 μL |
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| PLEKHA7-SMPD1-20-ORRE | 20 (40 μL) | 200 μL |
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| PLEKHA7-SMPD1-20-OROR | 20 (40 μL) | 200 μL |
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| PLEKHA7-SMPD1-20-ORGO | 20 (40 μL) | 200 μL |
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| PLEKHA7-SMPD1-20-ORAQ | 20 (40 μL) | 200 μL |
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| PLEKHA7-SMPD1-20-GORE | 20 (40 μL) | 200 μL |
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| PLEKHA7-SMPD1-20-GOOR | 20 (40 μL) | 200 μL |
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| PLEKHA7-SMPD1-20-GOGO | 20 (40 μL) | 200 μL |
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| PLEKHA7-SMPD1-20-GOGR | 20 (40 μL) | 200 μL |
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| PLEKHA7-SMPD1-20-GOAQ | 20 (40 μL) | 200 μL |
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| PLEKHA7-SMPD1-20-GRRE | 20 (40 μL) | 200 μL |
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| PLEKHA7-SMPD1-20-GROR | 20 (40 μL) | 200 μL |
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| PLEKHA7-SMPD1-20-GRGO | 20 (40 μL) | 200 μL |
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| PLEKHA7-SMPD1-20-GRGR | 20 (40 μL) | 200 μL |
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| PLEKHA7-SMPD1-20-GRAQ | 20 (40 μL) | 200 μL |
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| PLEKHA7-SMPD1-20-AQRE | 20 (40 μL) | 200 μL |
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| PLEKHA7-SMPD1-20-AQOR | 20 (40 μL) | 200 μL |
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| PLEKHA7-SMPD1-20-AQGO | 20 (40 μL) | 200 μL |
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| PLEKHA7-SMPD1-20-AQGR | 20 (40 μL) | 200 μL |
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| PLEKHA7-SMPD1-20-AQAQ | 20 (40 μL) | 200 μL |
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SMPD1 Gene Summary
The protein encoded by this gene is a lysosomal acid sphingomyelinase that converts sphingomyelin to ceramide. The encoded protein also has phospholipase C activity. Defects in this gene are a cause of Niemann-Pick disease type A (NPA) and Niemann-Pick disease type B (NPB). Multiple transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2010]
Gene Name: Sphingomyelin Phosphodiesterase 1
Chromosome: CHR11: 6411643 -6416228
Locus: 11p15.4
PLEKHA7 Gene Summary
The Pleckstrin Homology Domain Containing A7 (PLEKHA7) gene is located on chr11 :16809206-17035963 at 11p15.2-p15.1.
Gene Name: Pleckstrin Homology Domain Containing A7
Chromosome: CHR11: 16809206 -17035963
Locus: 11p15.2-p15.1
Gene Diseases
The PLEKHA7 SMPD1 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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