PLEKHA6-LRRN2 Fusion FISH Probe
The PLEKHA6-LRRN2 Fusion FISH Probe is used to confirm a fusion of the PLEKHA6 and LRRN2 genes. The fusion of the PLEKHA6 and LRRN2 genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PLEKHA6-LRRN2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PLEKHA6-LRRN2-20-RERE | 20 (40 μL) | 200 μL |
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| PLEKHA6-LRRN2-20-REOR | 20 (40 μL) | 200 μL |
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| PLEKHA6-LRRN2-20-REGO | 20 (40 μL) | 200 μL |
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| PLEKHA6-LRRN2-20-REGR | 20 (40 μL) | 200 μL |
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| PLEKHA6-LRRN2-20-REAQ | 20 (40 μL) | 200 μL |
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| PLEKHA6-LRRN2-20-ORRE | 20 (40 μL) | 200 μL |
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| PLEKHA6-LRRN2-20-OROR | 20 (40 μL) | 200 μL |
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| PLEKHA6-LRRN2-20-ORGO | 20 (40 μL) | 200 μL |
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| PLEKHA6-LRRN2-20-ORAQ | 20 (40 μL) | 200 μL |
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| PLEKHA6-LRRN2-20-GORE | 20 (40 μL) | 200 μL |
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| PLEKHA6-LRRN2-20-GOOR | 20 (40 μL) | 200 μL |
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| PLEKHA6-LRRN2-20-GOGO | 20 (40 μL) | 200 μL |
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| PLEKHA6-LRRN2-20-GOGR | 20 (40 μL) | 200 μL |
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| PLEKHA6-LRRN2-20-GOAQ | 20 (40 μL) | 200 μL |
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| PLEKHA6-LRRN2-20-GRRE | 20 (40 μL) | 200 μL |
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| PLEKHA6-LRRN2-20-GROR | 20 (40 μL) | 200 μL |
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| PLEKHA6-LRRN2-20-GRGO | 20 (40 μL) | 200 μL |
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| PLEKHA6-LRRN2-20-GRGR | 20 (40 μL) | 200 μL |
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| PLEKHA6-LRRN2-20-GRAQ | 20 (40 μL) | 200 μL |
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| PLEKHA6-LRRN2-20-AQRE | 20 (40 μL) | 200 μL |
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| PLEKHA6-LRRN2-20-AQOR | 20 (40 μL) | 200 μL |
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| PLEKHA6-LRRN2-20-AQGO | 20 (40 μL) | 200 μL |
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| PLEKHA6-LRRN2-20-AQGR | 20 (40 μL) | 200 μL |
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| PLEKHA6-LRRN2-20-AQAQ | 20 (40 μL) | 200 μL |
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LRRN2 Gene Summary
The protein encoded by this gene belongs to the leucine-rich repeat superfamily. This gene was found to be amplified and overexpressed in malignant gliomas. The encoded protein has homology with other proteins that function as cell-adhesion molecules or as signal transduction receptors and is a candidate for the target gene in the 1q32.1 amplicon in malignant gliomas. Two alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Leucine Rich Repeat Neuronal 2
Chromosome: CHR1: 204586302 -204654597
Locus: 1q32.1
PLEKHA6 Gene Summary
The Pleckstrin Homology Domain Containing A6 (PLEKHA6) gene is located on chr1 :204187980-204329044 at 1q32.1.
Gene Name: Pleckstrin Homology Domain Containing A6
Chromosome: CHR1: 204187980 -204329044
Locus: 1q32.1
Gene Diseases
The PLEKHA6 LRRN2 Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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