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PLEKHA3-MTX2 Fusion FISH Probe

The PLEKHA3-MTX2 Fusion FISH Probe is used to confirm a fusion of the PLEKHA3 and MTX2 genes. The fusion of the PLEKHA3 and MTX2 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
PLEKHA3-MTX2-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
PLEKHA3-MTX2-20-RERE 20 (40 μL) 200 μL
PLEKHA3-MTX2-20-REOR 20 (40 μL) 200 μL
PLEKHA3-MTX2-20-REGO 20 (40 μL) 200 μL
PLEKHA3-MTX2-20-REGR 20 (40 μL) 200 μL
PLEKHA3-MTX2-20-REAQ 20 (40 μL) 200 μL
PLEKHA3-MTX2-20-ORRE 20 (40 μL) 200 μL
PLEKHA3-MTX2-20-OROR 20 (40 μL) 200 μL
PLEKHA3-MTX2-20-ORGO 20 (40 μL) 200 μL
PLEKHA3-MTX2-20-ORAQ 20 (40 μL) 200 μL
PLEKHA3-MTX2-20-GORE 20 (40 μL) 200 μL
PLEKHA3-MTX2-20-GOOR 20 (40 μL) 200 μL
PLEKHA3-MTX2-20-GOGO 20 (40 μL) 200 μL
PLEKHA3-MTX2-20-GOGR 20 (40 μL) 200 μL
PLEKHA3-MTX2-20-GOAQ 20 (40 μL) 200 μL
PLEKHA3-MTX2-20-GRRE 20 (40 μL) 200 μL
PLEKHA3-MTX2-20-GROR 20 (40 μL) 200 μL
PLEKHA3-MTX2-20-GRGO 20 (40 μL) 200 μL
PLEKHA3-MTX2-20-GRGR 20 (40 μL) 200 μL
PLEKHA3-MTX2-20-GRAQ 20 (40 μL) 200 μL
PLEKHA3-MTX2-20-AQRE 20 (40 μL) 200 μL
PLEKHA3-MTX2-20-AQOR 20 (40 μL) 200 μL
PLEKHA3-MTX2-20-AQGO 20 (40 μL) 200 μL
PLEKHA3-MTX2-20-AQGR 20 (40 μL) 200 μL
PLEKHA3-MTX2-20-AQAQ 20 (40 μL) 200 μL

MTX2 Gene Summary

The protein encoded by this gene is highly similar to the metaxin 2 protein from mouse, which has been shown to interact with the mitochondrial membrane protein metaxin 1. Because of this similarity, it is thought that the encoded protein is peripherally associated with the cytosolic face of the outer mitochondrial membrane, and that it is involved in the import of proteins into the mitochondrion. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 7. [provided by RefSeq, Jun 2009]

Gene Name: Metaxin 2

Chromosome: CHR2: 177134122 -177202753

Locus: 2q31.1

PLEKHA3 Gene Summary

The Pleckstrin Homology Domain Containing A3 (PLEKHA3) gene is located on chr2 :179345198-179369782 at 2q31.2.

Gene Name: Pleckstrin Homology Domain Containing A3

Chromosome: CHR2: 179345198 -179369782

Locus: 2q31.2

Gene Diseases

The PLEKHA3 MTX2 Fusion has been associated with the following diseases:

Disease Name
Prostate Adenocarcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.