PLEKHA2-KCNU1 Fusion FISH Probe
The PLEKHA2-KCNU1 Fusion FISH Probe is used to confirm a fusion of the PLEKHA2 and KCNU1 genes. The fusion of the PLEKHA2 and KCNU1 genes has been associated with Breast Invasive Carcinoma, and Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PLEKHA2-KCNU1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PLEKHA2-KCNU1-20-RERE | 20 (40 μL) | 200 μL |
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| PLEKHA2-KCNU1-20-REOR | 20 (40 μL) | 200 μL |
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| PLEKHA2-KCNU1-20-REGO | 20 (40 μL) | 200 μL |
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| PLEKHA2-KCNU1-20-REGR | 20 (40 μL) | 200 μL |
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| PLEKHA2-KCNU1-20-REAQ | 20 (40 μL) | 200 μL |
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| PLEKHA2-KCNU1-20-ORRE | 20 (40 μL) | 200 μL |
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| PLEKHA2-KCNU1-20-OROR | 20 (40 μL) | 200 μL |
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| PLEKHA2-KCNU1-20-ORGO | 20 (40 μL) | 200 μL |
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| PLEKHA2-KCNU1-20-ORAQ | 20 (40 μL) | 200 μL |
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| PLEKHA2-KCNU1-20-GORE | 20 (40 μL) | 200 μL |
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| PLEKHA2-KCNU1-20-GOOR | 20 (40 μL) | 200 μL |
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| PLEKHA2-KCNU1-20-GOGO | 20 (40 μL) | 200 μL |
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| PLEKHA2-KCNU1-20-GOGR | 20 (40 μL) | 200 μL |
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| PLEKHA2-KCNU1-20-GOAQ | 20 (40 μL) | 200 μL |
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| PLEKHA2-KCNU1-20-GRRE | 20 (40 μL) | 200 μL |
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| PLEKHA2-KCNU1-20-GROR | 20 (40 μL) | 200 μL |
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| PLEKHA2-KCNU1-20-GRGO | 20 (40 μL) | 200 μL |
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| PLEKHA2-KCNU1-20-GRGR | 20 (40 μL) | 200 μL |
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| PLEKHA2-KCNU1-20-GRAQ | 20 (40 μL) | 200 μL |
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| PLEKHA2-KCNU1-20-AQRE | 20 (40 μL) | 200 μL |
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| PLEKHA2-KCNU1-20-AQOR | 20 (40 μL) | 200 μL |
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| PLEKHA2-KCNU1-20-AQGO | 20 (40 μL) | 200 μL |
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| PLEKHA2-KCNU1-20-AQGR | 20 (40 μL) | 200 μL |
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| PLEKHA2-KCNU1-20-AQAQ | 20 (40 μL) | 200 μL |
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PLEKHA2 Gene Summary
The Pleckstrin Homology Domain Containing A2 (PLEKHA2) gene is located on chr8 :38758752-38831430 at 8p11.22.
Gene Name: Pleckstrin Homology Domain Containing A2
Chromosome: CHR8: 38758752 -38831430
Locus: 8p11.22
KCNU1 Gene Summary
This gene encodes a member of the potassium channel family of proteins. The encoded voltage-gated ion channel allows the outward flow of potassium ions during plasma membrane hyperpolarization in sperm. Opening of this channel may be regulated by calcium ion levels. Homozygous knockout mice that lack the related mouse gene exhibit male sterility. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
Gene Name: Potassium Calcium-activated Channel Subfamily U Member 1
Chromosome: CHR8: 36641841 -36793643
Locus: 8p11.23
Gene Diseases
The PLEKHA2 KCNU1 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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