PLEKHA1-BTBD16 Fusion FISH Probe
The PLEKHA1-BTBD16 Fusion FISH Probe is used to confirm a fusion of the PLEKHA1 and BTBD16 genes. The fusion of the PLEKHA1 and BTBD16 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PLEKHA1-BTBD16-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PLEKHA1-BTBD16-20-RERE | 20 (40 μL) | 200 μL |
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| PLEKHA1-BTBD16-20-REOR | 20 (40 μL) | 200 μL |
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| PLEKHA1-BTBD16-20-REGO | 20 (40 μL) | 200 μL |
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| PLEKHA1-BTBD16-20-REGR | 20 (40 μL) | 200 μL |
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| PLEKHA1-BTBD16-20-REAQ | 20 (40 μL) | 200 μL |
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| PLEKHA1-BTBD16-20-ORRE | 20 (40 μL) | 200 μL |
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| PLEKHA1-BTBD16-20-OROR | 20 (40 μL) | 200 μL |
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| PLEKHA1-BTBD16-20-ORGO | 20 (40 μL) | 200 μL |
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| PLEKHA1-BTBD16-20-ORAQ | 20 (40 μL) | 200 μL |
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| PLEKHA1-BTBD16-20-GORE | 20 (40 μL) | 200 μL |
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| PLEKHA1-BTBD16-20-GOOR | 20 (40 μL) | 200 μL |
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| PLEKHA1-BTBD16-20-GOGO | 20 (40 μL) | 200 μL |
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| PLEKHA1-BTBD16-20-GOGR | 20 (40 μL) | 200 μL |
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| PLEKHA1-BTBD16-20-GOAQ | 20 (40 μL) | 200 μL |
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| PLEKHA1-BTBD16-20-GRRE | 20 (40 μL) | 200 μL |
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| PLEKHA1-BTBD16-20-GROR | 20 (40 μL) | 200 μL |
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| PLEKHA1-BTBD16-20-GRGO | 20 (40 μL) | 200 μL |
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| PLEKHA1-BTBD16-20-GRGR | 20 (40 μL) | 200 μL |
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| PLEKHA1-BTBD16-20-GRAQ | 20 (40 μL) | 200 μL |
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| PLEKHA1-BTBD16-20-AQRE | 20 (40 μL) | 200 μL |
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| PLEKHA1-BTBD16-20-AQOR | 20 (40 μL) | 200 μL |
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| PLEKHA1-BTBD16-20-AQGO | 20 (40 μL) | 200 μL |
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| PLEKHA1-BTBD16-20-AQGR | 20 (40 μL) | 200 μL |
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| PLEKHA1-BTBD16-20-AQAQ | 20 (40 μL) | 200 μL |
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PLEKHA1 Gene Summary
This gene encodes a pleckstrin homology domain-containing adapter protein. The encoded protein is localized to the plasma membrane where it specifically binds phosphatidylinositol 3,4-bisphosphate. This protein may be involved in the formation of signaling complexes in the plasma membrane. Polymorphisms in this gene are associated with age-related macular degeneration. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 5.[provided by RefSeq, Sep 2010]
Gene Name: Pleckstrin Homology Domain Containing A1
Chromosome: CHR10: 124134093 -124191871
Locus: 10q26.13
BTBD16 Gene Summary
This gene encodes a protein that contains a BTB/POZ domain. This domain mediates protein-protein interactions. A mutation in this gene may be associated with bipolar disorder. [provided by RefSeq, Sep 2016]
Gene Name: BTB Domain Containing 16
Chromosome: CHR10: 124030820 -124097676
Locus: 10q26.13
Gene Diseases
The PLEKHA1 BTBD16 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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