PLEK2-TMEM229B Fusion FISH Probe
The PLEK2-TMEM229B Fusion FISH Probe is used to confirm a fusion of the PLEK2 and TMEM229B genes. The fusion of the PLEK2 and TMEM229B genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PLEK2-TMEM229B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PLEK2-TMEM229B-20-RERE | 20 (40 μL) | 200 μL |
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| PLEK2-TMEM229B-20-REOR | 20 (40 μL) | 200 μL |
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| PLEK2-TMEM229B-20-REGO | 20 (40 μL) | 200 μL |
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| PLEK2-TMEM229B-20-REGR | 20 (40 μL) | 200 μL |
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| PLEK2-TMEM229B-20-REAQ | 20 (40 μL) | 200 μL |
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| PLEK2-TMEM229B-20-ORRE | 20 (40 μL) | 200 μL |
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| PLEK2-TMEM229B-20-OROR | 20 (40 μL) | 200 μL |
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| PLEK2-TMEM229B-20-ORGO | 20 (40 μL) | 200 μL |
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| PLEK2-TMEM229B-20-ORAQ | 20 (40 μL) | 200 μL |
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| PLEK2-TMEM229B-20-GORE | 20 (40 μL) | 200 μL |
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| PLEK2-TMEM229B-20-GOOR | 20 (40 μL) | 200 μL |
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| PLEK2-TMEM229B-20-GOGO | 20 (40 μL) | 200 μL |
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| PLEK2-TMEM229B-20-GOGR | 20 (40 μL) | 200 μL |
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| PLEK2-TMEM229B-20-GOAQ | 20 (40 μL) | 200 μL |
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| PLEK2-TMEM229B-20-GRRE | 20 (40 μL) | 200 μL |
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| PLEK2-TMEM229B-20-GROR | 20 (40 μL) | 200 μL |
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| PLEK2-TMEM229B-20-GRGO | 20 (40 μL) | 200 μL |
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| PLEK2-TMEM229B-20-GRGR | 20 (40 μL) | 200 μL |
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| PLEK2-TMEM229B-20-GRAQ | 20 (40 μL) | 200 μL |
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| PLEK2-TMEM229B-20-AQRE | 20 (40 μL) | 200 μL |
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| PLEK2-TMEM229B-20-AQOR | 20 (40 μL) | 200 μL |
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| PLEK2-TMEM229B-20-AQGO | 20 (40 μL) | 200 μL |
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| PLEK2-TMEM229B-20-AQGR | 20 (40 μL) | 200 μL |
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| PLEK2-TMEM229B-20-AQAQ | 20 (40 μL) | 200 μL |
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PLEK2 Gene Summary
The protein encoded by this gene associates with membrane-bound phosphatidylinositols generated by phosphatidylinositol 3-kinase. The encoded protein then interacts with the actin cytoskeleton to induce cell spreading. In conjunction with complement component 1, q subcomponent, B chain (C1QB), this gene shows an increase in expression in melanoma cells and may serve as an accurate biomarker for the disease. [provided by RefSeq, Dec 2015]
Gene Name: Pleckstrin 2
Chromosome: CHR14: 67853699 -67878828
Locus: 14q23.3-q24.1
TMEM229B Gene Summary
The Transmembrane Protein 229B (TMEM229B) gene is located on chr14 :67936982-67982021 at 14q24.1.
Gene Name: Transmembrane Protein 229B
Chromosome: CHR14: 67936982 -67982021
Locus: 14q24.1
Gene Diseases
The PLEK2 TMEM229B Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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