PLD3-NCALD Fusion FISH Probe
The PLD3-NCALD Fusion FISH Probe is used to confirm a fusion of the PLD3 and NCALD genes. The fusion of the PLD3 and NCALD genes has been associated with Kidney Renal Clear Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PLD3-NCALD-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| PLD3-NCALD-20-RERE | 20 (40 μL) | 200 μL |
|
|
| PLD3-NCALD-20-REOR | 20 (40 μL) | 200 μL |
|
|
| PLD3-NCALD-20-REGO | 20 (40 μL) | 200 μL |
|
|
| PLD3-NCALD-20-REGR | 20 (40 μL) | 200 μL |
|
|
| PLD3-NCALD-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| PLD3-NCALD-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| PLD3-NCALD-20-OROR | 20 (40 μL) | 200 μL |
|
|
| PLD3-NCALD-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| PLD3-NCALD-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| PLD3-NCALD-20-GORE | 20 (40 μL) | 200 μL |
|
|
| PLD3-NCALD-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| PLD3-NCALD-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| PLD3-NCALD-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| PLD3-NCALD-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| PLD3-NCALD-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| PLD3-NCALD-20-GROR | 20 (40 μL) | 200 μL |
|
|
| PLD3-NCALD-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| PLD3-NCALD-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| PLD3-NCALD-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| PLD3-NCALD-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| PLD3-NCALD-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| PLD3-NCALD-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| PLD3-NCALD-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| PLD3-NCALD-20-AQAQ | 20 (40 μL) | 200 μL |
|
PLD3 Gene Summary
This gene encodes a member of the phospholipase D (PLD) family of enzymes that catalyze the hydrolysis of membrane phospholipids. The encoded protein is a single-pass type II membrane protein and contains two PLD phosphodiesterase domains. This protein influences processing of amyloid-beta precursor protein. Mutations in this gene are associated with Alzheimer disease risk. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Apr 2014]
Gene Name: Phospholipase D Family Member 3
Chromosome: CHR19: 40854331 -40884390
Locus: 19q13.2
NCALD Gene Summary
This gene encodes a member of the neuronal calcium sensor (NCS) family of calcium-binding proteins. The protein contains an N-terminal myristoylation signal and four EF-hand calcium binding loops. The protein is cytosolic at resting calcium levels; however, elevated intracellular calcium levels induce a conformational change that exposes the myristoyl group, resulting in protein association with membranes and partial co-localization with the perinuclear trans-golgi network. The protein is thought to be a regulator of G protein-coupled receptor signal transduction. Several alternatively spliced variants of this gene have been determined, all of which encode the same protein; additional variants may exist but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
Gene Name: Neurocalcin Delta
Chromosome: CHR8: 102698769 -103137135
Locus: 8q22.3
Gene Diseases
The PLD3 NCALD Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Kidney Renal Clear Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|