PLD1-LMBR1 Fusion FISH Probe
The PLD1-LMBR1 Fusion FISH Probe is used to confirm a fusion of the PLD1 and LMBR1 genes. The fusion of the PLD1 and LMBR1 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PLD1-LMBR1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PLD1-LMBR1-20-RERE | 20 (40 μL) | 200 μL |
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| PLD1-LMBR1-20-REOR | 20 (40 μL) | 200 μL |
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| PLD1-LMBR1-20-REGO | 20 (40 μL) | 200 μL |
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| PLD1-LMBR1-20-REGR | 20 (40 μL) | 200 μL |
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| PLD1-LMBR1-20-REAQ | 20 (40 μL) | 200 μL |
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| PLD1-LMBR1-20-ORRE | 20 (40 μL) | 200 μL |
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| PLD1-LMBR1-20-OROR | 20 (40 μL) | 200 μL |
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| PLD1-LMBR1-20-ORGO | 20 (40 μL) | 200 μL |
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| PLD1-LMBR1-20-ORAQ | 20 (40 μL) | 200 μL |
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| PLD1-LMBR1-20-GORE | 20 (40 μL) | 200 μL |
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| PLD1-LMBR1-20-GOOR | 20 (40 μL) | 200 μL |
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| PLD1-LMBR1-20-GOGO | 20 (40 μL) | 200 μL |
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| PLD1-LMBR1-20-GOGR | 20 (40 μL) | 200 μL |
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| PLD1-LMBR1-20-GOAQ | 20 (40 μL) | 200 μL |
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| PLD1-LMBR1-20-GRRE | 20 (40 μL) | 200 μL |
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| PLD1-LMBR1-20-GROR | 20 (40 μL) | 200 μL |
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| PLD1-LMBR1-20-GRGO | 20 (40 μL) | 200 μL |
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| PLD1-LMBR1-20-GRGR | 20 (40 μL) | 200 μL |
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| PLD1-LMBR1-20-GRAQ | 20 (40 μL) | 200 μL |
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| PLD1-LMBR1-20-AQRE | 20 (40 μL) | 200 μL |
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| PLD1-LMBR1-20-AQOR | 20 (40 μL) | 200 μL |
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| PLD1-LMBR1-20-AQGO | 20 (40 μL) | 200 μL |
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| PLD1-LMBR1-20-AQGR | 20 (40 μL) | 200 μL |
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| PLD1-LMBR1-20-AQAQ | 20 (40 μL) | 200 μL |
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PLD1 Gene Summary
This gene encodes a phosphatidylcholine-specific phospholipase which catalyzes the hydrolysis of phosphatidylcholine in order to yield phosphatidic acid and choline. The enzyme may play a role in signal transduction and subcellular trafficking. Alternative splicing results in multiple transcript variants with both catalytic and regulatory properties. [provided by RefSeq, Sep 2011]
Gene Name: Phospholipase D1
Chromosome: CHR3: 171318194 -171528284
Locus: 3q26.31
LMBR1 Gene Summary
This gene encodes a member of the LMBR1-like membrane protein family. Another member of this protein family has been shown to be a lipocalin transmembrane receptor. A highly conserved, cis-acting regulatory module for the sonic hedgehog gene is located within an intron of this gene. Consequently, disruption of this genic region can alter sonic hedgehog expression and affect limb patterning, but it is not known if this gene functions directly in limb development. Mutations and chromosomal deletions and rearrangements in this genic region are associated with acheiropody and preaxial polydactyly, which likely result from altered sonic hedgehog expression. [provided by RefSeq, Jul 2008]
Gene Name: Limb Development Membrane Protein 1
Chromosome: CHR7: 156473569 -156685902
Locus: 7q36.3
Gene Diseases
The PLD1 LMBR1 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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