PLCB4-RASA3 Fusion FISH Probe
The PLCB4-RASA3 Fusion FISH Probe is used to confirm a fusion of the PLCB4 and RASA3 genes. The fusion of the PLCB4 and RASA3 genes has been associated with Rectum Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PLCB4-RASA3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PLCB4-RASA3-20-RERE | 20 (40 μL) | 200 μL |
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| PLCB4-RASA3-20-REOR | 20 (40 μL) | 200 μL |
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| PLCB4-RASA3-20-REGO | 20 (40 μL) | 200 μL |
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| PLCB4-RASA3-20-REGR | 20 (40 μL) | 200 μL |
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| PLCB4-RASA3-20-REAQ | 20 (40 μL) | 200 μL |
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| PLCB4-RASA3-20-ORRE | 20 (40 μL) | 200 μL |
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| PLCB4-RASA3-20-OROR | 20 (40 μL) | 200 μL |
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| PLCB4-RASA3-20-ORGO | 20 (40 μL) | 200 μL |
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| PLCB4-RASA3-20-ORAQ | 20 (40 μL) | 200 μL |
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| PLCB4-RASA3-20-GORE | 20 (40 μL) | 200 μL |
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| PLCB4-RASA3-20-GOOR | 20 (40 μL) | 200 μL |
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| PLCB4-RASA3-20-GOGO | 20 (40 μL) | 200 μL |
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| PLCB4-RASA3-20-GOGR | 20 (40 μL) | 200 μL |
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| PLCB4-RASA3-20-GOAQ | 20 (40 μL) | 200 μL |
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| PLCB4-RASA3-20-GRRE | 20 (40 μL) | 200 μL |
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| PLCB4-RASA3-20-GROR | 20 (40 μL) | 200 μL |
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| PLCB4-RASA3-20-GRGO | 20 (40 μL) | 200 μL |
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| PLCB4-RASA3-20-GRGR | 20 (40 μL) | 200 μL |
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| PLCB4-RASA3-20-GRAQ | 20 (40 μL) | 200 μL |
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| PLCB4-RASA3-20-AQRE | 20 (40 μL) | 200 μL |
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| PLCB4-RASA3-20-AQOR | 20 (40 μL) | 200 μL |
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| PLCB4-RASA3-20-AQGO | 20 (40 μL) | 200 μL |
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| PLCB4-RASA3-20-AQGR | 20 (40 μL) | 200 μL |
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| PLCB4-RASA3-20-AQAQ | 20 (40 μL) | 200 μL |
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PLCB4 Gene Summary
The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals in the retina. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2010]
Gene Name: Phospholipase C Beta 4
Chromosome: CHR20: 9049700 -9461462
Locus: 20p12.3-p12.2
RASA3 Gene Summary
This gene encodes a protein that binds inositol 1,3,4,5-tetrakisphosphate and stimulates the GTPase activity of Ras p21. This protein functions as a negative regulator of the Ras signalling pathway. It is localized to the cell membrane via a pleckstrin homology (PH) domain in the C-terminal region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
Gene Name: RAS P21 Protein Activator 3
Chromosome: CHR13: 114747193 -114898095
Locus: 13q34
Gene Diseases
The PLCB4 RASA3 Fusion has been associated with the following diseases:
| Disease Name |
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| Rectum Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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