PLAUR-ZNF576 Fusion FISH Probe
The PLAUR-ZNF576 Fusion FISH Probe is used to confirm a fusion of the PLAUR and ZNF576 genes. The fusion of the PLAUR and ZNF576 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PLAUR-ZNF576-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PLAUR-ZNF576-20-RERE | 20 (40 μL) | 200 μL |
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| PLAUR-ZNF576-20-REOR | 20 (40 μL) | 200 μL |
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| PLAUR-ZNF576-20-REGO | 20 (40 μL) | 200 μL |
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| PLAUR-ZNF576-20-REGR | 20 (40 μL) | 200 μL |
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| PLAUR-ZNF576-20-REAQ | 20 (40 μL) | 200 μL |
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| PLAUR-ZNF576-20-ORRE | 20 (40 μL) | 200 μL |
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| PLAUR-ZNF576-20-OROR | 20 (40 μL) | 200 μL |
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| PLAUR-ZNF576-20-ORGO | 20 (40 μL) | 200 μL |
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| PLAUR-ZNF576-20-ORAQ | 20 (40 μL) | 200 μL |
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| PLAUR-ZNF576-20-GORE | 20 (40 μL) | 200 μL |
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| PLAUR-ZNF576-20-GOOR | 20 (40 μL) | 200 μL |
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| PLAUR-ZNF576-20-GOGO | 20 (40 μL) | 200 μL |
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| PLAUR-ZNF576-20-GOGR | 20 (40 μL) | 200 μL |
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| PLAUR-ZNF576-20-GOAQ | 20 (40 μL) | 200 μL |
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| PLAUR-ZNF576-20-GRRE | 20 (40 μL) | 200 μL |
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| PLAUR-ZNF576-20-GROR | 20 (40 μL) | 200 μL |
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| PLAUR-ZNF576-20-GRGO | 20 (40 μL) | 200 μL |
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| PLAUR-ZNF576-20-GRGR | 20 (40 μL) | 200 μL |
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| PLAUR-ZNF576-20-GRAQ | 20 (40 μL) | 200 μL |
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| PLAUR-ZNF576-20-AQRE | 20 (40 μL) | 200 μL |
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| PLAUR-ZNF576-20-AQOR | 20 (40 μL) | 200 μL |
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| PLAUR-ZNF576-20-AQGO | 20 (40 μL) | 200 μL |
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| PLAUR-ZNF576-20-AQGR | 20 (40 μL) | 200 μL |
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| PLAUR-ZNF576-20-AQAQ | 20 (40 μL) | 200 μL |
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PLAUR Gene Summary
This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined. [provided by RefSeq, Jul 2008]
Gene Name: Plasminogen Activator, Urokinase Receptor
Chromosome: CHR19: 44150246 -44174498
Locus: 19q13.31
ZNF576 Gene Summary
The Zinc Finger Protein 576 (ZNF576) gene is located on chr19 :44100543-44104587 at 19q13.31.
Gene Name: Zinc Finger Protein 576
Chromosome: CHR19: 44100543 -44104587
Locus: 19q13.31
Gene Diseases
The PLAUR ZNF576 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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