PLA2G6-TMEM184B Fusion FISH Probe
The PLA2G6-TMEM184B Fusion FISH Probe is used to confirm a fusion of the PLA2G6 and TMEM184B genes. The fusion of the PLA2G6 and TMEM184B genes has been associated with Breast Invasive Carcinoma, and Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PLA2G6-TMEM184B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PLA2G6-TMEM184B-20-RERE | 20 (40 μL) | 200 μL |
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| PLA2G6-TMEM184B-20-REOR | 20 (40 μL) | 200 μL |
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| PLA2G6-TMEM184B-20-REGO | 20 (40 μL) | 200 μL |
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| PLA2G6-TMEM184B-20-REGR | 20 (40 μL) | 200 μL |
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| PLA2G6-TMEM184B-20-REAQ | 20 (40 μL) | 200 μL |
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| PLA2G6-TMEM184B-20-ORRE | 20 (40 μL) | 200 μL |
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| PLA2G6-TMEM184B-20-OROR | 20 (40 μL) | 200 μL |
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| PLA2G6-TMEM184B-20-ORGO | 20 (40 μL) | 200 μL |
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| PLA2G6-TMEM184B-20-ORAQ | 20 (40 μL) | 200 μL |
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| PLA2G6-TMEM184B-20-GORE | 20 (40 μL) | 200 μL |
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| PLA2G6-TMEM184B-20-GOOR | 20 (40 μL) | 200 μL |
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| PLA2G6-TMEM184B-20-GOGO | 20 (40 μL) | 200 μL |
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| PLA2G6-TMEM184B-20-GOGR | 20 (40 μL) | 200 μL |
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| PLA2G6-TMEM184B-20-GOAQ | 20 (40 μL) | 200 μL |
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| PLA2G6-TMEM184B-20-GRRE | 20 (40 μL) | 200 μL |
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| PLA2G6-TMEM184B-20-GROR | 20 (40 μL) | 200 μL |
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| PLA2G6-TMEM184B-20-GRGO | 20 (40 μL) | 200 μL |
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| PLA2G6-TMEM184B-20-GRGR | 20 (40 μL) | 200 μL |
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| PLA2G6-TMEM184B-20-GRAQ | 20 (40 μL) | 200 μL |
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| PLA2G6-TMEM184B-20-AQRE | 20 (40 μL) | 200 μL |
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| PLA2G6-TMEM184B-20-AQOR | 20 (40 μL) | 200 μL |
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| PLA2G6-TMEM184B-20-AQGO | 20 (40 μL) | 200 μL |
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| PLA2G6-TMEM184B-20-AQGR | 20 (40 μL) | 200 μL |
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| PLA2G6-TMEM184B-20-AQAQ | 20 (40 μL) | 200 μL |
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PLA2G6 Gene Summary
The protein encoded by this gene is an A2 phospholipase, a class of enzyme that catalyzes the release of fatty acids from phospholipids. The encoded protein may play a role in phospholipid remodelling, arachidonic acid release, leukotriene and prostaglandin synthesis, fas-mediated apoptosis, and transmembrane ion flux in glucose-stimulated B-cells. Several transcript variants encoding multiple isoforms have been described, but the full-length nature of only three of them have been determined to date. [provided by RefSeq, Dec 2010]
Gene Name: Phospholipase A2 Group VI
Chromosome: CHR22: 38507501 -38577836
Locus: 22q13.1
TMEM184B Gene Summary
The Transmembrane Protein 184B (TMEM184B) gene is located on chr22 :38615297-38669040 at 22q13.1.
Gene Name: Transmembrane Protein 184B
Chromosome: CHR22: 38615297 -38669040
Locus: 22q13.1
Gene Diseases
The PLA2G6 TMEM184B Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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