PLA2G2A-TAF15 Fusion FISH Probe
The PLA2G2A-TAF15 Fusion FISH Probe is used to confirm a fusion of the PLA2G2A and TAF15 genes. The fusion of the PLA2G2A and TAF15 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PLA2G2A-TAF15-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PLA2G2A-TAF15-20-RERE | 20 (40 μL) | 200 μL |
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| PLA2G2A-TAF15-20-REOR | 20 (40 μL) | 200 μL |
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| PLA2G2A-TAF15-20-REGO | 20 (40 μL) | 200 μL |
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| PLA2G2A-TAF15-20-REGR | 20 (40 μL) | 200 μL |
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| PLA2G2A-TAF15-20-REAQ | 20 (40 μL) | 200 μL |
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| PLA2G2A-TAF15-20-ORRE | 20 (40 μL) | 200 μL |
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| PLA2G2A-TAF15-20-OROR | 20 (40 μL) | 200 μL |
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| PLA2G2A-TAF15-20-ORGO | 20 (40 μL) | 200 μL |
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| PLA2G2A-TAF15-20-ORAQ | 20 (40 μL) | 200 μL |
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| PLA2G2A-TAF15-20-GORE | 20 (40 μL) | 200 μL |
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| PLA2G2A-TAF15-20-GOOR | 20 (40 μL) | 200 μL |
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| PLA2G2A-TAF15-20-GOGO | 20 (40 μL) | 200 μL |
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| PLA2G2A-TAF15-20-GOGR | 20 (40 μL) | 200 μL |
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| PLA2G2A-TAF15-20-GOAQ | 20 (40 μL) | 200 μL |
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| PLA2G2A-TAF15-20-GRRE | 20 (40 μL) | 200 μL |
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| PLA2G2A-TAF15-20-GROR | 20 (40 μL) | 200 μL |
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| PLA2G2A-TAF15-20-GRGO | 20 (40 μL) | 200 μL |
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| PLA2G2A-TAF15-20-GRGR | 20 (40 μL) | 200 μL |
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| PLA2G2A-TAF15-20-GRAQ | 20 (40 μL) | 200 μL |
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| PLA2G2A-TAF15-20-AQRE | 20 (40 μL) | 200 μL |
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| PLA2G2A-TAF15-20-AQOR | 20 (40 μL) | 200 μL |
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| PLA2G2A-TAF15-20-AQGO | 20 (40 μL) | 200 μL |
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| PLA2G2A-TAF15-20-AQGR | 20 (40 μL) | 200 μL |
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| PLA2G2A-TAF15-20-AQAQ | 20 (40 μL) | 200 μL |
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PLA2G2A Gene Summary
The protein encoded by this gene is a member of the phospholipase A2 family (PLA2). PLA2s constitute a diverse family of enzymes with respect to sequence, function, localization, and divalent cation requirements. This gene product belongs to group II, which contains secreted form of PLA2, an extracellular enzyme that has a low molecular mass and requires calcium ions for catalysis. It catalyzes the hydrolysis of the sn-2 fatty acid acyl ester bond of phosphoglycerides, releasing free fatty acids and lysophospholipids, and thought to participate in the regulation of the phospholipid metabolism in biomembranes. Several alternatively spliced transcript variants with different 5' UTRs have been found for this gene.[provided by RefSeq, Sep 2009]
Gene Name: Phospholipase A2 Group IIA
Chromosome: CHR1: 20301923 -20306932
Locus: 1p36.13
TAF15 Gene Summary
This gene encodes a member of the TET family of RNA-binding proteins. The encoded protein plays a role in RNA polymerase II gene transcription as a component of a distinct subset of multi-subunit transcription initiation factor TFIID complexes. Translocations involving this gene play a role in acute leukemia and extraskeletal myxoid chondrosarcoma, and mutations in this gene may play a role in amyotrophic lateral sclerosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]
Gene Name: TATA-box Binding Protein Associated Factor 15
Chromosome: CHR17: 34136487 -34174238
Locus: 17q12
Gene Diseases
The PLA2G2A TAF15 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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