PLA2G2A-FBLN1 Fusion FISH Probe
The PLA2G2A-FBLN1 Fusion FISH Probe is used to confirm a fusion of the PLA2G2A and FBLN1 genes. The fusion of the PLA2G2A and FBLN1 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
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PLA2G2A-FBLN1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL | ||
PLA2G2A-FBLN1-20-RERE | 20 (40 μL) | 200 μL | ||
PLA2G2A-FBLN1-20-REOR | 20 (40 μL) | 200 μL | ||
PLA2G2A-FBLN1-20-REGO | 20 (40 μL) | 200 μL | ||
PLA2G2A-FBLN1-20-REGR | 20 (40 μL) | 200 μL | ||
PLA2G2A-FBLN1-20-REAQ | 20 (40 μL) | 200 μL | ||
PLA2G2A-FBLN1-20-ORRE | 20 (40 μL) | 200 μL | ||
PLA2G2A-FBLN1-20-OROR | 20 (40 μL) | 200 μL | ||
PLA2G2A-FBLN1-20-ORGO | 20 (40 μL) | 200 μL | ||
PLA2G2A-FBLN1-20-ORAQ | 20 (40 μL) | 200 μL | ||
PLA2G2A-FBLN1-20-GORE | 20 (40 μL) | 200 μL | ||
PLA2G2A-FBLN1-20-GOOR | 20 (40 μL) | 200 μL | ||
PLA2G2A-FBLN1-20-GOGO | 20 (40 μL) | 200 μL | ||
PLA2G2A-FBLN1-20-GOGR | 20 (40 μL) | 200 μL | ||
PLA2G2A-FBLN1-20-GOAQ | 20 (40 μL) | 200 μL | ||
PLA2G2A-FBLN1-20-GRRE | 20 (40 μL) | 200 μL | ||
PLA2G2A-FBLN1-20-GROR | 20 (40 μL) | 200 μL | ||
PLA2G2A-FBLN1-20-GRGO | 20 (40 μL) | 200 μL | ||
PLA2G2A-FBLN1-20-GRGR | 20 (40 μL) | 200 μL | ||
PLA2G2A-FBLN1-20-GRAQ | 20 (40 μL) | 200 μL | ||
PLA2G2A-FBLN1-20-AQRE | 20 (40 μL) | 200 μL | ||
PLA2G2A-FBLN1-20-AQOR | 20 (40 μL) | 200 μL | ||
PLA2G2A-FBLN1-20-AQGO | 20 (40 μL) | 200 μL | ||
PLA2G2A-FBLN1-20-AQGR | 20 (40 μL) | 200 μL | ||
PLA2G2A-FBLN1-20-AQAQ | 20 (40 μL) | 200 μL |
FBLN1 Gene Summary
Fibulin 1 is a secreted glycoprotein that becomes incorporated into a fibrillar extracellular matrix. Calcium-binding is apparently required to mediate its binding to laminin and nidogen. It mediates platelet adhesion via binding fibrinogen. Four splice variants which differ in the 3' end have been identified. Each variant encodes a different isoform, but no functional distinctions have been identified among the four variants. [provided by RefSeq, Jul 2008]
Gene Name: Fibulin 1
Chromosome: CHR22: 45898718 -45997014
Locus: 22q13.31
PLA2G2A Gene Summary
The protein encoded by this gene is a member of the phospholipase A2 family (PLA2). PLA2s constitute a diverse family of enzymes with respect to sequence, function, localization, and divalent cation requirements. This gene product belongs to group II, which contains secreted form of PLA2, an extracellular enzyme that has a low molecular mass and requires calcium ions for catalysis. It catalyzes the hydrolysis of the sn-2 fatty acid acyl ester bond of phosphoglycerides, releasing free fatty acids and lysophospholipids, and thought to participate in the regulation of the phospholipid metabolism in biomembranes. Several alternatively spliced transcript variants with different 5' UTRs have been found for this gene.[provided by RefSeq, Sep 2009]
Gene Name: Phospholipase A2 Group IIA
Chromosome: CHR1: 20301923 -20306932
Locus: 1p36.13
Gene Diseases
The PLA2G2A FBLN1 Fusion has been associated with the following diseases:
Disease Name |
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Prostate Adenocarcinoma |
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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