PKNOX1-H2BFM Fusion FISH Probe
The PKNOX1-H2BFM Fusion FISH Probe is used to confirm a fusion of the PKNOX1 and H2BFM genes. The fusion of the PKNOX1 and H2BFM genes has been associated with Kidney Renal Clear Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PKNOX1-H2BFM-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PKNOX1-H2BFM-20-RERE | 20 (40 μL) | 200 μL |
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| PKNOX1-H2BFM-20-REOR | 20 (40 μL) | 200 μL |
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| PKNOX1-H2BFM-20-REGO | 20 (40 μL) | 200 μL |
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| PKNOX1-H2BFM-20-REGR | 20 (40 μL) | 200 μL |
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| PKNOX1-H2BFM-20-REAQ | 20 (40 μL) | 200 μL |
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| PKNOX1-H2BFM-20-ORRE | 20 (40 μL) | 200 μL |
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| PKNOX1-H2BFM-20-OROR | 20 (40 μL) | 200 μL |
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| PKNOX1-H2BFM-20-ORGO | 20 (40 μL) | 200 μL |
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| PKNOX1-H2BFM-20-ORAQ | 20 (40 μL) | 200 μL |
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| PKNOX1-H2BFM-20-GORE | 20 (40 μL) | 200 μL |
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| PKNOX1-H2BFM-20-GOOR | 20 (40 μL) | 200 μL |
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| PKNOX1-H2BFM-20-GOGO | 20 (40 μL) | 200 μL |
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| PKNOX1-H2BFM-20-GOGR | 20 (40 μL) | 200 μL |
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| PKNOX1-H2BFM-20-GOAQ | 20 (40 μL) | 200 μL |
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| PKNOX1-H2BFM-20-GRRE | 20 (40 μL) | 200 μL |
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| PKNOX1-H2BFM-20-GROR | 20 (40 μL) | 200 μL |
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| PKNOX1-H2BFM-20-GRGO | 20 (40 μL) | 200 μL |
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| PKNOX1-H2BFM-20-GRGR | 20 (40 μL) | 200 μL |
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| PKNOX1-H2BFM-20-GRAQ | 20 (40 μL) | 200 μL |
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| PKNOX1-H2BFM-20-AQRE | 20 (40 μL) | 200 μL |
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| PKNOX1-H2BFM-20-AQOR | 20 (40 μL) | 200 μL |
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| PKNOX1-H2BFM-20-AQGO | 20 (40 μL) | 200 μL |
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| PKNOX1-H2BFM-20-AQGR | 20 (40 μL) | 200 μL |
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| PKNOX1-H2BFM-20-AQAQ | 20 (40 μL) | 200 μL |
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PKNOX1 Gene Summary
The PBX/knotted 1 Homeobox 1 (PKNOX1) gene is located on chr21 :44394642-44453688 at 21q22.3.
Gene Name: PBX/knotted 1 Homeobox 1
Chromosome: CHR21: 44394642 -44453688
Locus: 21q22.3
H2BFM Gene Summary
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the H2B histone family. [provided by RefSeq, Nov 2015]
Gene Name: H2B Histone Family Member M
Chromosome: CHRX: 103294515 -103297021
Locus: Xq22.2
Gene Diseases
The PKNOX1 H2BFM Fusion has been associated with the following diseases:
| Disease Name |
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| Kidney Renal Clear Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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