PKIB-BLK Fusion FISH Probe
The PKIB-BLK Fusion FISH Probe is used to confirm a fusion of the PKIB and BLK genes. The fusion of the PKIB and BLK genes has been associated with Adrenocortical Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PKIB-BLK-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PKIB-BLK-20-RERE | 20 (40 μL) | 200 μL |
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| PKIB-BLK-20-REOR | 20 (40 μL) | 200 μL |
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| PKIB-BLK-20-REGO | 20 (40 μL) | 200 μL |
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| PKIB-BLK-20-REGR | 20 (40 μL) | 200 μL |
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| PKIB-BLK-20-REAQ | 20 (40 μL) | 200 μL |
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| PKIB-BLK-20-ORRE | 20 (40 μL) | 200 μL |
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| PKIB-BLK-20-OROR | 20 (40 μL) | 200 μL |
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| PKIB-BLK-20-ORGO | 20 (40 μL) | 200 μL |
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| PKIB-BLK-20-ORAQ | 20 (40 μL) | 200 μL |
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| PKIB-BLK-20-GORE | 20 (40 μL) | 200 μL |
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| PKIB-BLK-20-GOOR | 20 (40 μL) | 200 μL |
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| PKIB-BLK-20-GOGO | 20 (40 μL) | 200 μL |
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| PKIB-BLK-20-GOGR | 20 (40 μL) | 200 μL |
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| PKIB-BLK-20-GOAQ | 20 (40 μL) | 200 μL |
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| PKIB-BLK-20-GRRE | 20 (40 μL) | 200 μL |
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| PKIB-BLK-20-GROR | 20 (40 μL) | 200 μL |
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| PKIB-BLK-20-GRGO | 20 (40 μL) | 200 μL |
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| PKIB-BLK-20-GRGR | 20 (40 μL) | 200 μL |
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| PKIB-BLK-20-GRAQ | 20 (40 μL) | 200 μL |
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| PKIB-BLK-20-AQRE | 20 (40 μL) | 200 μL |
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| PKIB-BLK-20-AQOR | 20 (40 μL) | 200 μL |
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| PKIB-BLK-20-AQGO | 20 (40 μL) | 200 μL |
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| PKIB-BLK-20-AQGR | 20 (40 μL) | 200 μL |
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| PKIB-BLK-20-AQAQ | 20 (40 μL) | 200 μL |
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BLK Gene Summary
This gene encodes a nonreceptor tyrosine-kinase of the src family of proto-oncogenes that are typically involved in cell proliferation and differentiation. The protein has a role in B-cell receptor signaling and B-cell development. The protein also stimulates insulin synthesis and secretion in response to glucose and enhances the expression of several pancreatic beta-cell transcription factors. [provided by RefSeq, Aug 2010]
Gene Name: BLK Proto-oncogene, Src Family Tyrosine Kinase
Chromosome: CHR8: 11351520 -11422108
Locus: 8p23.1
PKIB Gene Summary
This gene encodes a member of the cAMP-dependent protein kinase inhibitor family. The encoded protein may play a role in the protein kinase A (PKA) pathway by interacting with the catalytic subunit of PKA, and overexpression of this gene may play a role in prostate cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]
Gene Name: CAMP-dependent Protein Kinase Inhibitor Beta
Chromosome: CHR6: 122793061 -123047518
Locus: 6q22.31
Gene Diseases
The PKIB BLK Fusion has been associated with the following diseases:
| Disease Name |
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| Adrenocortical Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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