PITPNM3-STX8 Fusion FISH Probe
The PITPNM3-STX8 Fusion FISH Probe is used to confirm a fusion of the PITPNM3 and STX8 genes. The fusion of the PITPNM3 and STX8 genes has been associated with Kidney Renal Clear Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PITPNM3-STX8-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PITPNM3-STX8-20-RERE | 20 (40 μL) | 200 μL |
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| PITPNM3-STX8-20-REOR | 20 (40 μL) | 200 μL |
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| PITPNM3-STX8-20-REGO | 20 (40 μL) | 200 μL |
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| PITPNM3-STX8-20-REGR | 20 (40 μL) | 200 μL |
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| PITPNM3-STX8-20-REAQ | 20 (40 μL) | 200 μL |
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| PITPNM3-STX8-20-ORRE | 20 (40 μL) | 200 μL |
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| PITPNM3-STX8-20-OROR | 20 (40 μL) | 200 μL |
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| PITPNM3-STX8-20-ORGO | 20 (40 μL) | 200 μL |
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| PITPNM3-STX8-20-ORAQ | 20 (40 μL) | 200 μL |
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| PITPNM3-STX8-20-GORE | 20 (40 μL) | 200 μL |
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| PITPNM3-STX8-20-GOOR | 20 (40 μL) | 200 μL |
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| PITPNM3-STX8-20-GOGO | 20 (40 μL) | 200 μL |
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| PITPNM3-STX8-20-GOGR | 20 (40 μL) | 200 μL |
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| PITPNM3-STX8-20-GOAQ | 20 (40 μL) | 200 μL |
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| PITPNM3-STX8-20-GRRE | 20 (40 μL) | 200 μL |
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| PITPNM3-STX8-20-GROR | 20 (40 μL) | 200 μL |
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| PITPNM3-STX8-20-GRGO | 20 (40 μL) | 200 μL |
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| PITPNM3-STX8-20-GRGR | 20 (40 μL) | 200 μL |
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| PITPNM3-STX8-20-GRAQ | 20 (40 μL) | 200 μL |
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| PITPNM3-STX8-20-AQRE | 20 (40 μL) | 200 μL |
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| PITPNM3-STX8-20-AQOR | 20 (40 μL) | 200 μL |
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| PITPNM3-STX8-20-AQGO | 20 (40 μL) | 200 μL |
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| PITPNM3-STX8-20-AQGR | 20 (40 μL) | 200 μL |
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| PITPNM3-STX8-20-AQAQ | 20 (40 μL) | 200 μL |
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STX8 Gene Summary
The gene is a member of the syntaxin family. The encoded protein is involved in protein trafficking from early to late endosomes via vesicle fusion and exocytosis. A related pseudogene has been identified on chromosome 12. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
Gene Name: Syntaxin 8
Chromosome: CHR17: 9153787 -9479275
Locus: 17p13.1
PITPNM3 Gene Summary
This gene encodes a member of a family of membrane-associated phosphatidylinositol transfer domain-containing proteins. The calcium-binding protein has phosphatidylinositol (PI) transfer activity and interacts with the protein tyrosine kinase PTK2B (also known as PYK2). The protein is homologous to a Drosophila protein that is implicated in the visual transduction pathway in flies. Mutations in this gene result in autosomal dominant cone dystrophy. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]
Gene Name: PITPNM Family Member 3
Chromosome: CHR17: 6354582 -6459877
Locus: 17p13.2-p13.1
Gene Diseases
The PITPNM3 STX8 Fusion has been associated with the following diseases:
| Disease Name |
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| Kidney Renal Clear Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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