PIP4K2B-SLC6A4 Fusion FISH Probe
The PIP4K2B-SLC6A4 Fusion FISH Probe is used to confirm a fusion of the PIP4K2B and SLC6A4 genes. The fusion of the PIP4K2B and SLC6A4 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PIP4K2B-SLC6A4-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| PIP4K2B-SLC6A4-20-RERE | 20 (40 μL) | 200 μL |
|
|
| PIP4K2B-SLC6A4-20-REOR | 20 (40 μL) | 200 μL |
|
|
| PIP4K2B-SLC6A4-20-REGO | 20 (40 μL) | 200 μL |
|
|
| PIP4K2B-SLC6A4-20-REGR | 20 (40 μL) | 200 μL |
|
|
| PIP4K2B-SLC6A4-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| PIP4K2B-SLC6A4-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| PIP4K2B-SLC6A4-20-OROR | 20 (40 μL) | 200 μL |
|
|
| PIP4K2B-SLC6A4-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| PIP4K2B-SLC6A4-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| PIP4K2B-SLC6A4-20-GORE | 20 (40 μL) | 200 μL |
|
|
| PIP4K2B-SLC6A4-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| PIP4K2B-SLC6A4-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| PIP4K2B-SLC6A4-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| PIP4K2B-SLC6A4-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| PIP4K2B-SLC6A4-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| PIP4K2B-SLC6A4-20-GROR | 20 (40 μL) | 200 μL |
|
|
| PIP4K2B-SLC6A4-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| PIP4K2B-SLC6A4-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| PIP4K2B-SLC6A4-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| PIP4K2B-SLC6A4-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| PIP4K2B-SLC6A4-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| PIP4K2B-SLC6A4-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| PIP4K2B-SLC6A4-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| PIP4K2B-SLC6A4-20-AQAQ | 20 (40 μL) | 200 μL |
|
SLC6A4 Gene Summary
This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma. [provided by RefSeq, Jul 2008]
Gene Name: Solute Carrier Family 6 Member 4
Chromosome: CHR17: 28523377 -28562954
Locus: 17q11.2
PIP4K2B Gene Summary
The protein encoded by this gene catalyzes the phosphorylation of phosphatidylinositol-5-phosphate on the fourth hydroxyl of the myo-inositol ring to form phosphatidylinositol-5,4-bisphosphate. This gene is a member of the phosphatidylinositol-5-phosphate 4-kinase family. The encoded protein sequence does not show similarity to other kinases, but the protein does exhibit kinase activity. Additionally, the encoded protein interacts with p55 TNF receptor. [provided by RefSeq, Jul 2008]
Gene Name: Phosphatidylinositol-5-phosphate 4-kinase Type 2 Beta
Chromosome: CHR17: 36921943 -36956158
Locus: 17q12
Gene Diseases
The PIP4K2B SLC6A4 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|