PILRB-IMMP2L Fusion FISH Probe
The PILRB-IMMP2L Fusion FISH Probe is used to confirm a fusion of the PILRB and IMMP2L genes. The fusion of the PILRB and IMMP2L genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PILRB-IMMP2L-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PILRB-IMMP2L-20-RERE | 20 (40 μL) | 200 μL |
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| PILRB-IMMP2L-20-REOR | 20 (40 μL) | 200 μL |
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| PILRB-IMMP2L-20-REGO | 20 (40 μL) | 200 μL |
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| PILRB-IMMP2L-20-REGR | 20 (40 μL) | 200 μL |
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| PILRB-IMMP2L-20-REAQ | 20 (40 μL) | 200 μL |
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| PILRB-IMMP2L-20-ORRE | 20 (40 μL) | 200 μL |
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| PILRB-IMMP2L-20-OROR | 20 (40 μL) | 200 μL |
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| PILRB-IMMP2L-20-ORGO | 20 (40 μL) | 200 μL |
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| PILRB-IMMP2L-20-ORAQ | 20 (40 μL) | 200 μL |
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| PILRB-IMMP2L-20-GORE | 20 (40 μL) | 200 μL |
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| PILRB-IMMP2L-20-GOOR | 20 (40 μL) | 200 μL |
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| PILRB-IMMP2L-20-GOGO | 20 (40 μL) | 200 μL |
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| PILRB-IMMP2L-20-GOGR | 20 (40 μL) | 200 μL |
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| PILRB-IMMP2L-20-GOAQ | 20 (40 μL) | 200 μL |
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| PILRB-IMMP2L-20-GRRE | 20 (40 μL) | 200 μL |
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| PILRB-IMMP2L-20-GROR | 20 (40 μL) | 200 μL |
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| PILRB-IMMP2L-20-GRGO | 20 (40 μL) | 200 μL |
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| PILRB-IMMP2L-20-GRGR | 20 (40 μL) | 200 μL |
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| PILRB-IMMP2L-20-GRAQ | 20 (40 μL) | 200 μL |
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| PILRB-IMMP2L-20-AQRE | 20 (40 μL) | 200 μL |
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| PILRB-IMMP2L-20-AQOR | 20 (40 μL) | 200 μL |
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| PILRB-IMMP2L-20-AQGO | 20 (40 μL) | 200 μL |
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| PILRB-IMMP2L-20-AQGR | 20 (40 μL) | 200 μL |
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| PILRB-IMMP2L-20-AQAQ | 20 (40 μL) | 200 μL |
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PILRB Gene Summary
The paired immunoglobin-like type 2 receptors consist of highly related activating and inhibitory receptors that are involved in the regulation of many aspects of the immune system. The paired immunoglobulin-like receptor genes are located in a tandem head-to-tail orientation on chromosome 7. This gene encodes the activating member of the receptor pair and contains a truncated cytoplasmic tail relative to its inhibitory counterpart (PILRA), that has a long cytoplasmic tail with immunoreceptor tyrosine-based inhibitory (ITIM) motifs. This gene is thought to have arisen from a duplication of the inhibitory PILRA gene and evolved to acquire its activating function. [provided by RefSeq, Jun 2013]
Gene Name: Paired Immunoglobin-like Type 2 Receptor Beta
Chromosome: CHR7: 99933687 -99965454
Locus: 7q22.1
IMMP2L Gene Summary
This gene encodes a protein involved in processing the signal peptide sequences used to direct mitochondrial proteins to the mitochondria. The encoded protein resides in the mitochondria and is one of the necessary proteins for the catalytic activity of the mitochondrial inner membrane peptidase (IMP) complex. Two variants that encode the same protein have been described for this gene. [provided by RefSeq, Sep 2011]
Gene Name: Inner Mitochondrial Membrane Peptidase Subunit 2
Chromosome: CHR7: 110303109 -111202347
Locus: 7q31.1
Gene Diseases
The PILRB IMMP2L Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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