PIK3R3-ZSWIM5 Fusion FISH Probe
The PIK3R3-ZSWIM5 Fusion FISH Probe is used to confirm a fusion of the PIK3R3 and ZSWIM5 genes. The fusion of the PIK3R3 and ZSWIM5 genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PIK3R3-ZSWIM5-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PIK3R3-ZSWIM5-20-RERE | 20 (40 μL) | 200 μL |
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| PIK3R3-ZSWIM5-20-REOR | 20 (40 μL) | 200 μL |
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| PIK3R3-ZSWIM5-20-REGO | 20 (40 μL) | 200 μL |
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| PIK3R3-ZSWIM5-20-REGR | 20 (40 μL) | 200 μL |
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| PIK3R3-ZSWIM5-20-REAQ | 20 (40 μL) | 200 μL |
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| PIK3R3-ZSWIM5-20-ORRE | 20 (40 μL) | 200 μL |
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| PIK3R3-ZSWIM5-20-OROR | 20 (40 μL) | 200 μL |
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| PIK3R3-ZSWIM5-20-ORGO | 20 (40 μL) | 200 μL |
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| PIK3R3-ZSWIM5-20-ORAQ | 20 (40 μL) | 200 μL |
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| PIK3R3-ZSWIM5-20-GORE | 20 (40 μL) | 200 μL |
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| PIK3R3-ZSWIM5-20-GOOR | 20 (40 μL) | 200 μL |
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| PIK3R3-ZSWIM5-20-GOGO | 20 (40 μL) | 200 μL |
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| PIK3R3-ZSWIM5-20-GOGR | 20 (40 μL) | 200 μL |
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| PIK3R3-ZSWIM5-20-GOAQ | 20 (40 μL) | 200 μL |
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| PIK3R3-ZSWIM5-20-GRRE | 20 (40 μL) | 200 μL |
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| PIK3R3-ZSWIM5-20-GROR | 20 (40 μL) | 200 μL |
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| PIK3R3-ZSWIM5-20-GRGO | 20 (40 μL) | 200 μL |
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| PIK3R3-ZSWIM5-20-GRGR | 20 (40 μL) | 200 μL |
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| PIK3R3-ZSWIM5-20-GRAQ | 20 (40 μL) | 200 μL |
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| PIK3R3-ZSWIM5-20-AQRE | 20 (40 μL) | 200 μL |
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| PIK3R3-ZSWIM5-20-AQOR | 20 (40 μL) | 200 μL |
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| PIK3R3-ZSWIM5-20-AQGO | 20 (40 μL) | 200 μL |
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| PIK3R3-ZSWIM5-20-AQGR | 20 (40 μL) | 200 μL |
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| PIK3R3-ZSWIM5-20-AQAQ | 20 (40 μL) | 200 μL |
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PIK3R3 Gene Summary
Phosphatidylinositol 3-kinase (PI3K) phosphorylates phosphatidylinositol and similar compounds, which then serve as second messengers in growth signaling pathways. PI3K is composed of a catalytic and a regulatory subunit. The protein encoded by this gene represents a regulatory subunit of PI3K. The encoded protein contains two SH2 domains through which it binds activated protein tyrosine kinases to regulate their activity. [provided by RefSeq, Jun 2016]
Gene Name: Phosphoinositide-3-kinase Regulatory Subunit 3
Chromosome: CHR1: 46505811 -46598708
Locus: 1p34.1
ZSWIM5 Gene Summary
The Zinc Finger SWIM-type Containing 5 (ZSWIM5) gene is located on chr1 :45482075-45672250 at 1p34.1.
Gene Name: Zinc Finger SWIM-type Containing 5
Chromosome: CHR1: 45482075 -45672250
Locus: 1p34.1
Gene Diseases
The PIK3R3 ZSWIM5 Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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