PIK3R3-MYO18A Fusion FISH Probe
The PIK3R3-MYO18A Fusion FISH Probe is used to confirm a fusion of the PIK3R3 and MYO18A genes. The fusion of the PIK3R3 and MYO18A genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PIK3R3-MYO18A-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PIK3R3-MYO18A-20-RERE | 20 (40 μL) | 200 μL |
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| PIK3R3-MYO18A-20-REOR | 20 (40 μL) | 200 μL |
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| PIK3R3-MYO18A-20-REGO | 20 (40 μL) | 200 μL |
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| PIK3R3-MYO18A-20-REGR | 20 (40 μL) | 200 μL |
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| PIK3R3-MYO18A-20-REAQ | 20 (40 μL) | 200 μL |
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| PIK3R3-MYO18A-20-ORRE | 20 (40 μL) | 200 μL |
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| PIK3R3-MYO18A-20-OROR | 20 (40 μL) | 200 μL |
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| PIK3R3-MYO18A-20-ORGO | 20 (40 μL) | 200 μL |
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| PIK3R3-MYO18A-20-ORAQ | 20 (40 μL) | 200 μL |
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| PIK3R3-MYO18A-20-GORE | 20 (40 μL) | 200 μL |
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| PIK3R3-MYO18A-20-GOOR | 20 (40 μL) | 200 μL |
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| PIK3R3-MYO18A-20-GOGO | 20 (40 μL) | 200 μL |
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| PIK3R3-MYO18A-20-GOGR | 20 (40 μL) | 200 μL |
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| PIK3R3-MYO18A-20-GOAQ | 20 (40 μL) | 200 μL |
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| PIK3R3-MYO18A-20-GRRE | 20 (40 μL) | 200 μL |
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| PIK3R3-MYO18A-20-GROR | 20 (40 μL) | 200 μL |
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| PIK3R3-MYO18A-20-GRGO | 20 (40 μL) | 200 μL |
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| PIK3R3-MYO18A-20-GRGR | 20 (40 μL) | 200 μL |
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| PIK3R3-MYO18A-20-GRAQ | 20 (40 μL) | 200 μL |
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| PIK3R3-MYO18A-20-AQRE | 20 (40 μL) | 200 μL |
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| PIK3R3-MYO18A-20-AQOR | 20 (40 μL) | 200 μL |
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| PIK3R3-MYO18A-20-AQGO | 20 (40 μL) | 200 μL |
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| PIK3R3-MYO18A-20-AQGR | 20 (40 μL) | 200 μL |
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| PIK3R3-MYO18A-20-AQAQ | 20 (40 μL) | 200 μL |
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PIK3R3 Gene Summary
Phosphatidylinositol 3-kinase (PI3K) phosphorylates phosphatidylinositol and similar compounds, which then serve as second messengers in growth signaling pathways. PI3K is composed of a catalytic and a regulatory subunit. The protein encoded by this gene represents a regulatory subunit of PI3K. The encoded protein contains two SH2 domains through which it binds activated protein tyrosine kinases to regulate their activity. [provided by RefSeq, Jun 2016]
Gene Name: Phosphoinositide-3-kinase Regulatory Subunit 3
Chromosome: CHR1: 46505811 -46598708
Locus: 1p34.1
MYO18A Gene Summary
The protein encoded by this gene can bind GOLPH3, linking the Golgi to the cytoskeleton and influencing Golgi membrane trafficking. The encoded protein is also part of a complex that assembles lamellar actomyosin bundles and may be required for cell migration. [provided by RefSeq, Oct 2016]
Gene Name: Myosin XVIIIA
Chromosome: CHR17: 27400527 -27507407
Locus: 17q11.2
Gene Diseases
The PIK3R3 MYO18A Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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