PIGU-ACSS2 Fusion FISH Probe
The PIGU-ACSS2 Fusion FISH Probe is used to confirm a fusion of the PIGU and ACSS2 genes. The fusion of the PIGU and ACSS2 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PIGU-ACSS2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PIGU-ACSS2-20-RERE | 20 (40 μL) | 200 μL |
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| PIGU-ACSS2-20-REOR | 20 (40 μL) | 200 μL |
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| PIGU-ACSS2-20-REGO | 20 (40 μL) | 200 μL |
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| PIGU-ACSS2-20-REGR | 20 (40 μL) | 200 μL |
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| PIGU-ACSS2-20-REAQ | 20 (40 μL) | 200 μL |
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| PIGU-ACSS2-20-ORRE | 20 (40 μL) | 200 μL |
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| PIGU-ACSS2-20-OROR | 20 (40 μL) | 200 μL |
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| PIGU-ACSS2-20-ORGO | 20 (40 μL) | 200 μL |
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| PIGU-ACSS2-20-ORAQ | 20 (40 μL) | 200 μL |
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| PIGU-ACSS2-20-GORE | 20 (40 μL) | 200 μL |
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| PIGU-ACSS2-20-GOOR | 20 (40 μL) | 200 μL |
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| PIGU-ACSS2-20-GOGO | 20 (40 μL) | 200 μL |
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| PIGU-ACSS2-20-GOGR | 20 (40 μL) | 200 μL |
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| PIGU-ACSS2-20-GOAQ | 20 (40 μL) | 200 μL |
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| PIGU-ACSS2-20-GRRE | 20 (40 μL) | 200 μL |
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| PIGU-ACSS2-20-GROR | 20 (40 μL) | 200 μL |
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| PIGU-ACSS2-20-GRGO | 20 (40 μL) | 200 μL |
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| PIGU-ACSS2-20-GRGR | 20 (40 μL) | 200 μL |
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| PIGU-ACSS2-20-GRAQ | 20 (40 μL) | 200 μL |
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| PIGU-ACSS2-20-AQRE | 20 (40 μL) | 200 μL |
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| PIGU-ACSS2-20-AQOR | 20 (40 μL) | 200 μL |
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| PIGU-ACSS2-20-AQGO | 20 (40 μL) | 200 μL |
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| PIGU-ACSS2-20-AQGR | 20 (40 μL) | 200 μL |
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| PIGU-ACSS2-20-AQAQ | 20 (40 μL) | 200 μL |
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ACSS2 Gene Summary
This gene encodes a cytosolic enzyme that catalyzes the activation of acetate for use in lipid synthesis and energy generation. The protein acts as a monomer and produces acetyl-CoA from acetate in a reaction that requires ATP. Expression of this gene is regulated by sterol regulatory element-binding proteins, transcription factors that activate genes required for the synthesis of cholesterol and unsaturated fatty acids. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2009]
Gene Name: Acyl-CoA Synthetase Short Chain Family Member 2
Chromosome: CHR20: 33462765 -33515769
Locus: 20q11.22
PIGU Gene Summary
The protein encoded by this gene shares similarity with Saccharomyces cerevisiae Cdc91, a predicted integral membrane protein that may function in cell division control. The protein encoded by this gene is the fifth subunit of GPI transamidase that attaches GPI-anchors to proteins. [provided by RefSeq, Jul 2008]
Gene Name: Phosphatidylinositol Glycan Anchor Biosynthesis Class U
Chromosome: CHR20: 33148345 -33265089
Locus: 20q11.22
Gene Diseases
The PIGU ACSS2 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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