PIGK-TGFBR3 Fusion FISH Probe
The PIGK-TGFBR3 Fusion FISH Probe is used to confirm a fusion of the PIGK and TGFBR3 genes. The fusion of the PIGK and TGFBR3 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PIGK-TGFBR3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PIGK-TGFBR3-20-RERE | 20 (40 μL) | 200 μL |
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| PIGK-TGFBR3-20-REOR | 20 (40 μL) | 200 μL |
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| PIGK-TGFBR3-20-REGO | 20 (40 μL) | 200 μL |
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| PIGK-TGFBR3-20-REGR | 20 (40 μL) | 200 μL |
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| PIGK-TGFBR3-20-REAQ | 20 (40 μL) | 200 μL |
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| PIGK-TGFBR3-20-ORRE | 20 (40 μL) | 200 μL |
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| PIGK-TGFBR3-20-OROR | 20 (40 μL) | 200 μL |
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| PIGK-TGFBR3-20-ORGO | 20 (40 μL) | 200 μL |
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| PIGK-TGFBR3-20-ORAQ | 20 (40 μL) | 200 μL |
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| PIGK-TGFBR3-20-GORE | 20 (40 μL) | 200 μL |
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| PIGK-TGFBR3-20-GOOR | 20 (40 μL) | 200 μL |
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| PIGK-TGFBR3-20-GOGO | 20 (40 μL) | 200 μL |
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| PIGK-TGFBR3-20-GOGR | 20 (40 μL) | 200 μL |
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| PIGK-TGFBR3-20-GOAQ | 20 (40 μL) | 200 μL |
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| PIGK-TGFBR3-20-GRRE | 20 (40 μL) | 200 μL |
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| PIGK-TGFBR3-20-GROR | 20 (40 μL) | 200 μL |
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| PIGK-TGFBR3-20-GRGO | 20 (40 μL) | 200 μL |
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| PIGK-TGFBR3-20-GRGR | 20 (40 μL) | 200 μL |
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| PIGK-TGFBR3-20-GRAQ | 20 (40 μL) | 200 μL |
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| PIGK-TGFBR3-20-AQRE | 20 (40 μL) | 200 μL |
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| PIGK-TGFBR3-20-AQOR | 20 (40 μL) | 200 μL |
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| PIGK-TGFBR3-20-AQGO | 20 (40 μL) | 200 μL |
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| PIGK-TGFBR3-20-AQGR | 20 (40 μL) | 200 μL |
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| PIGK-TGFBR3-20-AQAQ | 20 (40 μL) | 200 μL |
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TGFBR3 Gene Summary
This locus encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.[provided by RefSeq, Sep 2010]
Gene Name: Transforming Growth Factor Beta Receptor 3
Chromosome: CHR1: 92145899 -92371559
Locus: 1p22.1
PIGK Gene Summary
This gene encodes a member of the cysteine protease family C13 that is involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This protein is a member of the multisubunit enzyme, GPI transamidase and is thought to be its enzymatic component. GPI transamidase mediates GPI anchoring in the endoplasmic reticulum, by catalyzing the transfer of fully assembled GPI units to proteins. [provided by RefSeq, Jul 2008]
Gene Name: Phosphatidylinositol Glycan Anchor Biosynthesis Class K
Chromosome: CHR1: 77554666 -77685132
Locus: 1p31.1
Gene Diseases
The PIGK TGFBR3 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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