PI4KB-SYT11 Fusion FISH Probe
The PI4KB-SYT11 Fusion FISH Probe is used to confirm a fusion of the PI4KB and SYT11 genes. The fusion of the PI4KB and SYT11 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PI4KB-SYT11-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PI4KB-SYT11-20-RERE | 20 (40 μL) | 200 μL |
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| PI4KB-SYT11-20-REOR | 20 (40 μL) | 200 μL |
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| PI4KB-SYT11-20-REGO | 20 (40 μL) | 200 μL |
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| PI4KB-SYT11-20-REGR | 20 (40 μL) | 200 μL |
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| PI4KB-SYT11-20-REAQ | 20 (40 μL) | 200 μL |
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| PI4KB-SYT11-20-ORRE | 20 (40 μL) | 200 μL |
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| PI4KB-SYT11-20-OROR | 20 (40 μL) | 200 μL |
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| PI4KB-SYT11-20-ORGO | 20 (40 μL) | 200 μL |
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| PI4KB-SYT11-20-ORAQ | 20 (40 μL) | 200 μL |
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| PI4KB-SYT11-20-GORE | 20 (40 μL) | 200 μL |
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| PI4KB-SYT11-20-GOOR | 20 (40 μL) | 200 μL |
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| PI4KB-SYT11-20-GOGO | 20 (40 μL) | 200 μL |
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| PI4KB-SYT11-20-GOGR | 20 (40 μL) | 200 μL |
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| PI4KB-SYT11-20-GOAQ | 20 (40 μL) | 200 μL |
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| PI4KB-SYT11-20-GRRE | 20 (40 μL) | 200 μL |
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| PI4KB-SYT11-20-GROR | 20 (40 μL) | 200 μL |
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| PI4KB-SYT11-20-GRGO | 20 (40 μL) | 200 μL |
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| PI4KB-SYT11-20-GRGR | 20 (40 μL) | 200 μL |
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| PI4KB-SYT11-20-GRAQ | 20 (40 μL) | 200 μL |
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| PI4KB-SYT11-20-AQRE | 20 (40 μL) | 200 μL |
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| PI4KB-SYT11-20-AQOR | 20 (40 μL) | 200 μL |
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| PI4KB-SYT11-20-AQGO | 20 (40 μL) | 200 μL |
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| PI4KB-SYT11-20-AQGR | 20 (40 μL) | 200 μL |
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| PI4KB-SYT11-20-AQAQ | 20 (40 μL) | 200 μL |
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PI4KB Gene Summary
The Phosphatidylinositol 4-kinase Beta (PI4KB) gene is located on chr1 :151264272-151300191 at 1q21.3.
Gene Name: Phosphatidylinositol 4-kinase Beta
Chromosome: CHR1: 151264272 -151300191
Locus: 1q21.3
SYT11 Gene Summary
This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that are known calcium sensors and mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. The encoded protein is also a substrate for ubiquitin-E3-ligase parkin. The gene has previously been referred to as synaptotagmin XII but has been renamed synaptotagmin XI to be consistent with mouse and rat official nomenclature. [provided by RefSeq, Apr 2010]
Gene Name: Synaptotagmin 11
Chromosome: CHR1: 155829259 -155854990
Locus: 1q22
Gene Diseases
The PI4KB SYT11 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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