PI4KA-ZNF274 Fusion FISH Probe
The PI4KA-ZNF274 Fusion FISH Probe is used to confirm a fusion of the PI4KA and ZNF274 genes. The fusion of the PI4KA and ZNF274 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PI4KA-ZNF274-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PI4KA-ZNF274-20-RERE | 20 (40 μL) | 200 μL |
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| PI4KA-ZNF274-20-REOR | 20 (40 μL) | 200 μL |
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| PI4KA-ZNF274-20-REGO | 20 (40 μL) | 200 μL |
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| PI4KA-ZNF274-20-REGR | 20 (40 μL) | 200 μL |
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| PI4KA-ZNF274-20-REAQ | 20 (40 μL) | 200 μL |
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| PI4KA-ZNF274-20-ORRE | 20 (40 μL) | 200 μL |
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| PI4KA-ZNF274-20-OROR | 20 (40 μL) | 200 μL |
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| PI4KA-ZNF274-20-ORGO | 20 (40 μL) | 200 μL |
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| PI4KA-ZNF274-20-ORAQ | 20 (40 μL) | 200 μL |
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| PI4KA-ZNF274-20-GORE | 20 (40 μL) | 200 μL |
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| PI4KA-ZNF274-20-GOOR | 20 (40 μL) | 200 μL |
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| PI4KA-ZNF274-20-GOGO | 20 (40 μL) | 200 μL |
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| PI4KA-ZNF274-20-GOGR | 20 (40 μL) | 200 μL |
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| PI4KA-ZNF274-20-GOAQ | 20 (40 μL) | 200 μL |
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| PI4KA-ZNF274-20-GRRE | 20 (40 μL) | 200 μL |
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| PI4KA-ZNF274-20-GROR | 20 (40 μL) | 200 μL |
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| PI4KA-ZNF274-20-GRGO | 20 (40 μL) | 200 μL |
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| PI4KA-ZNF274-20-GRGR | 20 (40 μL) | 200 μL |
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| PI4KA-ZNF274-20-GRAQ | 20 (40 μL) | 200 μL |
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| PI4KA-ZNF274-20-AQRE | 20 (40 μL) | 200 μL |
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| PI4KA-ZNF274-20-AQOR | 20 (40 μL) | 200 μL |
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| PI4KA-ZNF274-20-AQGO | 20 (40 μL) | 200 μL |
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| PI4KA-ZNF274-20-AQGR | 20 (40 μL) | 200 μL |
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| PI4KA-ZNF274-20-AQAQ | 20 (40 μL) | 200 μL |
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PI4KA Gene Summary
This gene encodes a phosphatidylinositol (PI) 4-kinase which catalyzes the first committed step in the biosynthesis of phosphatidylinositol 4,5-bisphosphate. The mammalian PI 4-kinases have been classified into two types, II and III, based on their molecular mass, and modulation by detergent and adenosine. The protein encoded by this gene is a type III enzyme that is not inhibited by adenosine. [provided by RefSeq, Sep 2014]
Gene Name: Phosphatidylinositol 4-kinase Alpha
Chromosome: CHR22: 21061978 -21213070
Locus: 22q11.21
ZNF274 Gene Summary
This gene encodes a zinc finger protein containing five C2H2-type zinc finger domains, one or two Kruppel-associated box A (KRAB A) domains, and a leucine-rich domain. The encoded protein has been suggested to be a transcriptional repressor. It localizes predominantly to the nucleolus. Alternatively spliced transcript variants encoding different isoforms exist. These variants utilize alternative polyadenylation signals. [provided by RefSeq, Jul 2008]
Gene Name: Zinc Finger Protein 274
Chromosome: CHR19: 58694395 -58724927
Locus: 19q13.43
Gene Diseases
The PI4KA ZNF274 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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