PI4K2A-UBTD1 Fusion FISH Probe
The PI4K2A-UBTD1 Fusion FISH Probe is used to confirm a fusion of the PI4K2A and UBTD1 genes. The fusion of the PI4K2A and UBTD1 genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PI4K2A-UBTD1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PI4K2A-UBTD1-20-RERE | 20 (40 μL) | 200 μL |
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| PI4K2A-UBTD1-20-REOR | 20 (40 μL) | 200 μL |
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| PI4K2A-UBTD1-20-REGO | 20 (40 μL) | 200 μL |
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| PI4K2A-UBTD1-20-REGR | 20 (40 μL) | 200 μL |
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| PI4K2A-UBTD1-20-REAQ | 20 (40 μL) | 200 μL |
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| PI4K2A-UBTD1-20-ORRE | 20 (40 μL) | 200 μL |
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| PI4K2A-UBTD1-20-OROR | 20 (40 μL) | 200 μL |
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| PI4K2A-UBTD1-20-ORGO | 20 (40 μL) | 200 μL |
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| PI4K2A-UBTD1-20-ORAQ | 20 (40 μL) | 200 μL |
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| PI4K2A-UBTD1-20-GORE | 20 (40 μL) | 200 μL |
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| PI4K2A-UBTD1-20-GOOR | 20 (40 μL) | 200 μL |
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| PI4K2A-UBTD1-20-GOGO | 20 (40 μL) | 200 μL |
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| PI4K2A-UBTD1-20-GOGR | 20 (40 μL) | 200 μL |
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| PI4K2A-UBTD1-20-GOAQ | 20 (40 μL) | 200 μL |
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| PI4K2A-UBTD1-20-GRRE | 20 (40 μL) | 200 μL |
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| PI4K2A-UBTD1-20-GROR | 20 (40 μL) | 200 μL |
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| PI4K2A-UBTD1-20-GRGO | 20 (40 μL) | 200 μL |
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| PI4K2A-UBTD1-20-GRGR | 20 (40 μL) | 200 μL |
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| PI4K2A-UBTD1-20-GRAQ | 20 (40 μL) | 200 μL |
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| PI4K2A-UBTD1-20-AQRE | 20 (40 μL) | 200 μL |
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| PI4K2A-UBTD1-20-AQOR | 20 (40 μL) | 200 μL |
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| PI4K2A-UBTD1-20-AQGO | 20 (40 μL) | 200 μL |
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| PI4K2A-UBTD1-20-AQGR | 20 (40 μL) | 200 μL |
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| PI4K2A-UBTD1-20-AQAQ | 20 (40 μL) | 200 μL |
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PI4K2A Gene Summary
Phosphatidylinositolpolyphosphates (PtdInsPs) are centrally involved in many biologic processes, ranging from cell growth and organization of the actin cytoskeleton to endo- and exocytosis. PI4KII phosphorylates PtdIns at the D-4 position, an essential step in the biosynthesis of PtdInsPs (Barylko et al., 2001 [PubMed 11244087]).[supplied by OMIM, Mar 2008]
Gene Name: Phosphatidylinositol 4-kinase Type 2 Alpha
Chromosome: CHR10: 99400442 -99436187
Locus: 10q24.2
UBTD1 Gene Summary
The degradation of many proteins is carried out by the ubiquitin pathway in which proteins are targeted for degradation by covalent conjugation of the polypeptide ubiquitin. This gene encodes a protein that belongs to the ubiquitin family of proteins. The encoded protein is thought to regulate E2 ubiquitin conjugating enzymes belonging to the UBE2D family. [provided by RefSeq, Mar 2014]
Gene Name: Ubiquitin Domain Containing 1
Chromosome: CHR10: 99258767 -99330960
Locus: 10q24.1-q24.2
Gene Diseases
The PI4K2A UBTD1 Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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