PHLPP1-ADAMTS13 Fusion FISH Probe
The PHLPP1-ADAMTS13 Fusion FISH Probe is used to confirm a fusion of the PHLPP1 and ADAMTS13 genes. The fusion of the PHLPP1 and ADAMTS13 genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PHLPP1-ADAMTS13-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PHLPP1-ADAMTS13-20-RERE | 20 (40 μL) | 200 μL |
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| PHLPP1-ADAMTS13-20-REOR | 20 (40 μL) | 200 μL |
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| PHLPP1-ADAMTS13-20-REGO | 20 (40 μL) | 200 μL |
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| PHLPP1-ADAMTS13-20-REGR | 20 (40 μL) | 200 μL |
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| PHLPP1-ADAMTS13-20-REAQ | 20 (40 μL) | 200 μL |
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| PHLPP1-ADAMTS13-20-ORRE | 20 (40 μL) | 200 μL |
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| PHLPP1-ADAMTS13-20-OROR | 20 (40 μL) | 200 μL |
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| PHLPP1-ADAMTS13-20-ORGO | 20 (40 μL) | 200 μL |
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| PHLPP1-ADAMTS13-20-ORAQ | 20 (40 μL) | 200 μL |
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| PHLPP1-ADAMTS13-20-GORE | 20 (40 μL) | 200 μL |
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| PHLPP1-ADAMTS13-20-GOOR | 20 (40 μL) | 200 μL |
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| PHLPP1-ADAMTS13-20-GOGO | 20 (40 μL) | 200 μL |
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| PHLPP1-ADAMTS13-20-GOGR | 20 (40 μL) | 200 μL |
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| PHLPP1-ADAMTS13-20-GOAQ | 20 (40 μL) | 200 μL |
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| PHLPP1-ADAMTS13-20-GRRE | 20 (40 μL) | 200 μL |
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| PHLPP1-ADAMTS13-20-GROR | 20 (40 μL) | 200 μL |
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| PHLPP1-ADAMTS13-20-GRGO | 20 (40 μL) | 200 μL |
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| PHLPP1-ADAMTS13-20-GRGR | 20 (40 μL) | 200 μL |
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| PHLPP1-ADAMTS13-20-GRAQ | 20 (40 μL) | 200 μL |
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| PHLPP1-ADAMTS13-20-AQRE | 20 (40 μL) | 200 μL |
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| PHLPP1-ADAMTS13-20-AQOR | 20 (40 μL) | 200 μL |
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| PHLPP1-ADAMTS13-20-AQGO | 20 (40 μL) | 200 μL |
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| PHLPP1-ADAMTS13-20-AQGR | 20 (40 μL) | 200 μL |
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| PHLPP1-ADAMTS13-20-AQAQ | 20 (40 μL) | 200 μL |
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ADAMTS13 Gene Summary
This gene encodes a member of a family of proteins containing several distinct regions, including a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. The enzyme encoded by this gene specifically cleaves von Willebrand Factor (vWF). Defects in this gene are associated with thrombotic thrombocytopenic purpura. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Gene Name: ADAM Metallopeptidase With Thrombospondin Type 1 Motif 13
Chromosome: CHR9: 136279458 -136324508
Locus: 9q34.2
PHLPP1 Gene Summary
This gene encodes a member of the serine/threonine phosphatase family. The encoded protein promotes apoptosis by dephosphorylating and inactivating the serine/threonine kinase Akt, and functions as a tumor suppressor in multiple types of cancer. Increased expression of this gene may also play a role in obesity and type 2 diabetes by interfering with Akt-mediated insulin signaling. [provided by RefSeq, Dec 2011]
Gene Name: PH Domain And Leucine Rich Repeat Protein Phosphatase 1
Chromosome: CHR18: 60382671 -60647666
Locus: 18q21.33
Gene Diseases
The PHLPP1 ADAMTS13 Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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