PHLDB2-RIMS2 Fusion FISH Probe
The PHLDB2-RIMS2 Fusion FISH Probe is used to confirm a fusion of the PHLDB2 and RIMS2 genes. The fusion of the PHLDB2 and RIMS2 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PHLDB2-RIMS2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PHLDB2-RIMS2-20-RERE | 20 (40 μL) | 200 μL |
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| PHLDB2-RIMS2-20-REOR | 20 (40 μL) | 200 μL |
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| PHLDB2-RIMS2-20-REGO | 20 (40 μL) | 200 μL |
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| PHLDB2-RIMS2-20-REGR | 20 (40 μL) | 200 μL |
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| PHLDB2-RIMS2-20-REAQ | 20 (40 μL) | 200 μL |
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| PHLDB2-RIMS2-20-ORRE | 20 (40 μL) | 200 μL |
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| PHLDB2-RIMS2-20-OROR | 20 (40 μL) | 200 μL |
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| PHLDB2-RIMS2-20-ORGO | 20 (40 μL) | 200 μL |
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| PHLDB2-RIMS2-20-ORAQ | 20 (40 μL) | 200 μL |
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| PHLDB2-RIMS2-20-GORE | 20 (40 μL) | 200 μL |
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| PHLDB2-RIMS2-20-GOOR | 20 (40 μL) | 200 μL |
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| PHLDB2-RIMS2-20-GOGO | 20 (40 μL) | 200 μL |
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| PHLDB2-RIMS2-20-GOGR | 20 (40 μL) | 200 μL |
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| PHLDB2-RIMS2-20-GOAQ | 20 (40 μL) | 200 μL |
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| PHLDB2-RIMS2-20-GRRE | 20 (40 μL) | 200 μL |
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| PHLDB2-RIMS2-20-GROR | 20 (40 μL) | 200 μL |
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| PHLDB2-RIMS2-20-GRGO | 20 (40 μL) | 200 μL |
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| PHLDB2-RIMS2-20-GRGR | 20 (40 μL) | 200 μL |
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| PHLDB2-RIMS2-20-GRAQ | 20 (40 μL) | 200 μL |
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| PHLDB2-RIMS2-20-AQRE | 20 (40 μL) | 200 μL |
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| PHLDB2-RIMS2-20-AQOR | 20 (40 μL) | 200 μL |
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| PHLDB2-RIMS2-20-AQGO | 20 (40 μL) | 200 μL |
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| PHLDB2-RIMS2-20-AQGR | 20 (40 μL) | 200 μL |
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| PHLDB2-RIMS2-20-AQAQ | 20 (40 μL) | 200 μL |
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RIMS2 Gene Summary
The protein encoded by this gene is a presynaptic protein that interacts with RAB3, a protein important for normal neurotransmitter release. The encoded protein can also bind several other synaptic proteins, including UNC-13 homolog B, ELKS/Rab6-interacting/CAST family member 1, and synaptotagmin 1. This protein is involved in synaptic membrane exocytosis. Polymorphisms in this gene have been associated with degenerative lumbar scoliosis. [provided by RefSeq, Feb 2017]
Gene Name: Regulating Synaptic Membrane Exocytosis 2
Chromosome: CHR8: 104512975 -105266656
Locus: 8q22.3
PHLDB2 Gene Summary
The Pleckstrin Homology Like Domain Family B Member 2 (PHLDB2) gene is located on chr3 :111451326-111695364 at 3q13.2.
Gene Name: Pleckstrin Homology Like Domain Family B Member 2
Chromosome: CHR3: 111451326 -111695364
Locus: 3q13.2
Gene Diseases
The PHLDB2 RIMS2 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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